Trace Element Speciation Laboratory Aberdeen (TESLA), Department of Chemistry, University of Aberdeen, Aberdeen, Scotland, UK.
Chemistry Department, College of Science, University of Jeddah, Jeddah, Saudi Arabia.
Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2024 Jul;41(7):856-866. doi: 10.1080/19440049.2024.2347491. Epub 2024 May 10.
Food contact materials (FCMs) from three countries were analysed for all extractable organofluorines (EOFs) from the materials and subsequently by target and non-target analysis for per- and polyfluoroalkyl substances (PFAS). The EOF varied by two orders of magnitude for FCM from UK and Saudi Arabia ranging between 2.14 and 483 ng cm (0.2-48 ng g) showing that one quarter of all samples were above the Danish regulation for PFAS in FCM. Target PFAS showed high variability in composition and accounted for less than 1% of the EOF. Non-target PFAS screening using HPLC-ICP-MS and coupled simultaneously to HRMS showed the occurrence of organofluorines which were identified by neither LC-MS/MS nor LC-HRMS. This illustrates that the current target PFAS approaches fail to identify EOFs from FCM, which would be a problem with the new EU proposal to ban all PFAS.
对来自三个国家的食品接触材料（FCM）进行了所有可萃取有机氟（EOF）的分析，并随后通过目标和非目标分析对全氟和多氟烷基物质（PFAS）进行了分析。来自英国和沙特阿拉伯的 FCM 的 EOF 变化幅度为两个数量级，范围在 2.14 至 483ng·cm（0.2-48ng·g）之间，表明四分之一的所有样品中的 PFAS 含量均高于丹麦对 FCM 中 PFAS 的规定。目标 PFAS 的组成具有高度可变性，仅占 EOF 的不到 1%。使用 HPLC-ICP-MS 进行的非目标 PFAS 筛选，并同时与 HRMS 耦合，显示出既没有 LC-MS/MS 也没有 LC-HRMS 鉴定出的有机氟的存在。这表明，目前的目标 PFAS 方法无法识别 FCM 中的 EOF，如果欧盟新提案禁止所有 PFAS，这将是一个问题。
