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诊断和管理肾移植受者的尿路感染。

Diagnosing and Managing Urinary Tract Infections in Kidney Transplant Recipients.

机构信息

Division of Pediatric Nephrology, Johns Hopkins University School of Medicine; Division of Pediatric Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

Division of Pediatric Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

出版信息

Infect Dis Clin North Am. 2024 Jun;38(2):361-380. doi: 10.1016/j.idc.2024.03.008.

DOI:10.1016/j.idc.2024.03.008
PMID:38729666
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11090456/
Abstract

In the article, the authors review antibiotic treatment options for both acute uncomplicated UTI and complicated UTI. In addition, they review alternative regimens which are needed in the setting of drug-resistant pathogens including vancomycin-resistant Enterococcus, -extended-spectrum beta-lactamase-producing Enterobacterales (ESBL-E), carbapenem-resistant Enterobacterales, and carbapenem-resistant Pseudomonas, which are encountered with more frequency.

摘要

在这篇文章中,作者回顾了急性单纯性尿路感染和复杂性尿路感染的抗生素治疗选择。此外,他们还回顾了在耐药病原体(包括耐万古霉素肠球菌、产超广谱β-内酰胺酶的肠杆菌科细菌、碳青霉烯类耐药肠杆菌科细菌和碳青霉烯类耐药铜绿假单胞菌)存在时需要的替代方案,这些病原体的出现频率越来越高。

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Diagnosing and Managing Urinary Tract Infections in Kidney Transplant Recipients.诊断和管理肾移植受者的尿路感染。
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2
Unitary Tract Infection Treatment: When to Use What Agents including Beta-lactam Combination Agents.单一部位尿路感染的治疗:何时使用何种药物,包括β-内酰胺类联合药物。
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ESBL-producing enterobacteriaceae-related urinary tract infections in kidney transplant recipients: incidence and risk factors for recurrence.产超广谱β-内酰胺酶肠杆菌科相关尿路感染在肾移植受者中的发生率和复发的危险因素。
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A five-year retrospective study focused on urinary tract infections in kidney transplant recipients in the current era of immunosuppression.一项为期五年的回顾性研究聚焦于免疫抑制当前时代肾移植受者的尿路感染。
Front Med (Lausanne). 2025 Jul 22;12:1606224. doi: 10.3389/fmed.2025.1606224. eCollection 2025.
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Providing care for kidney transplant recipients: An overview for generalists.为肾移植受者提供护理:全科医生概述
World J Nephrol. 2025 Mar 25;14(1):99555. doi: 10.5527/wjn.v14.i1.99555.
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The role of metagenomic next-generation sequencing in diagnosing and managing post-kidney transplantation infections.

本文引用的文献

1
Prevalence and risk factors of urinary tract infection in kidney recipients: a meta-analysis study.肾移植受者尿路感染的患病率及危险因素:一项荟萃分析研究。
BMC Nephrol. 2023 Sep 27;24(1):284. doi: 10.1186/s12882-023-03338-4.
2
Delayed Graft Function Among Kidney Transplant Recipients Is Associated With an Increased Risk of Urinary Tract Infection and BK Viremia.肾移植受者的移植肾功能延迟与尿路感染和BK病毒血症风险增加相关。
Transplant Direct. 2023 Aug 28;9(9):e1526. doi: 10.1097/TXD.0000000000001526. eCollection 2023 Sep.
3
Infectious Diseases Society of America 2023 Guidance on the Treatment of Antimicrobial Resistant Gram-Negative Infections.
宏基因组下一代测序在肾移植后感染的诊断和管理中的作用。
Front Cell Infect Microbiol. 2025 Jan 7;14:1473068. doi: 10.3389/fcimb.2024.1473068. eCollection 2024.
美国传染病学会2023年抗微生物药物耐药革兰氏阴性菌感染治疗指南
Clin Infect Dis. 2023 Jul 18. doi: 10.1093/cid/ciad428.
4
Therapeutic Potential of Intravenous Phage as Standalone Therapy for Recurrent Drug-Resistant Urinary Tract Infections.静脉噬菌体作为单独疗法治疗复发性耐药性尿路感染的治疗潜力。
Antimicrob Agents Chemother. 2023 Apr 18;67(4):e0003723. doi: 10.1128/aac.00037-23. Epub 2023 Mar 28.
5
Asymptomatic Bacteriuria in Kidney Transplant Recipients-A Narrative Review.无症状性菌尿症在肾移植受者中的研究进展:一项叙述性综述。
Medicina (Kaunas). 2023 Jan 19;59(2):198. doi: 10.3390/medicina59020198.
6
Defining the Optimal Duration of Therapy for Hospitalized Patients With Complicated Urinary Tract Infections and Associated Bacteremia.定义合并菌血症的住院复杂性尿路感染患者的最佳治疗持续时间。
Clin Infect Dis. 2023 May 3;76(9):1604-1612. doi: 10.1093/cid/ciad009.
7
BK Virus Nephropathy in Kidney Transplantation: A State-of-the-Art Review.BK 病毒肾病在肾移植中的研究进展:一篇综述。
Viruses. 2022 Jul 25;14(8):1616. doi: 10.3390/v14081616.
8
Acute kidney injury secondary to urinary tract infection in kidney transplant recipients.肾移植受者继发于尿路感染的急性肾损伤。
Sci Rep. 2022 Jun 27;12(1):10858. doi: 10.1038/s41598-022-15035-7.
9
Extended-spectrum β-lactamase-producing and carbapenem-resistant Enterobacterales bloodstream infection after solid organ transplantation: Recent trends in epidemiology and therapeutic approaches.移植术后产超广谱β-内酰胺酶和碳青霉烯类耐药肠杆菌科血流感染:流行病学和治疗方法的最新趋势。
Transpl Infect Dis. 2022 Aug;24(4):e13881. doi: 10.1111/tid.13881. Epub 2022 Jun 28.
10
Impact of different urinary tract infection phenotypes within the first year post-transplant on renal allograft outcomes.移植后 1 年内不同尿路感染表型对肾移植结局的影响。
Am J Transplant. 2022 Jul;22(7):1823-1833. doi: 10.1111/ajt.17026. Epub 2022 Mar 26.