Hofmann Amun Georg, Mlekusch Irene, Wickenhauser Georg, Walter Corinna, Taher Fadi, Assadian Afshin
Department of Vascular and Endovascular Surgery, Klinik Ottakring, Montleartstraße 37, 1160 Vienna, Austria.
Diagnostics (Basel). 2024 Apr 29;14(9):930. doi: 10.3390/diagnostics14090930.
Surveillance after endovascular aortic repair (EVAR) and fenestrated EVAR (FEVAR) is mainly directed by one-size-fits-all approaches instead of personalized decision making, even though treatment strategies and often endografts themselves are tailor-made to adjust for individual patients. We propose a modular imaging algorithm that escalates surveillance imaging based on invasiveness and need.
In this retrospective observational study of single-center data, results of a modular imaging algorithm were analyzed. The algorithm is characterized by initiating the examination with standard B-mode then transitioning to Duplex ultrasound, B-Flow, and CEUS. Additional CT(A) studies are conducted where required. The study population included both patients receiving EVAR or FEVAR. A comparative analysis was conducted regarding endoleak detection.
The study population included 28 patients receiving EVAR and 40 patients receiving FEVAR. They accounted for 101 follow-up visits, which led to 431 distinct imaging studies. CEUS has the highest endoleak detection rate, followed by CTA and B-Flow. Duplex ultrasound and B-Flow resulted in 0 and 1 false positive cases, respectively, considering CEUS the reference standard. In a select group of six patients, CEUS was omitted after endoleaks were displayed by Duplex ultrasound or B-Flow, leading to a successful type II coiling and no aneurysm-related adverse events.
The proposed modular algorithm showed great potential to incorporate principles of personalized medicine in surveillance after endovascular aortic treatment. Since Duplex ultrasound and B-Flow rarely cause false positive endoleaks, more resource-intensive and invasive imaging studies such as CEUS and CTA can be omitted after positive identification.
尽管血管内主动脉修复术(EVAR)和开窗型血管内主动脉修复术(FEVAR)的治疗策略甚至移植物本身通常都是为个体患者量身定制的,但术后监测主要采用一刀切的方法,而非个性化决策。我们提出一种模块化成像算法,根据侵入性和需求逐步升级监测成像。
在这项对单中心数据的回顾性观察研究中,分析了一种模块化成像算法的结果。该算法的特点是先进行标准B模式检查,然后过渡到双功超声、B-Flow和CEUS。根据需要进行额外的CT(A)检查。研究人群包括接受EVAR或FEVAR的患者。对内漏检测进行了对比分析。
研究人群包括28例接受EVAR的患者和40例接受FEVAR的患者。他们进行了101次随访,共进行了431项不同的成像研究。CEUS的内漏检测率最高,其次是CTA和B-Flow。以CEUS为参考标准,双功超声和B-Flow分别导致0例和1例假阳性病例。在一组6例患者中,双功超声或B-Flow显示内漏后省略了CEUS,成功进行了II型弹簧圈栓塞,且未发生与动脉瘤相关的不良事件。
所提出的模块化算法在血管内主动脉治疗后的监测中具有将个性化医疗原则纳入其中的巨大潜力。由于双功超声和B-Flow很少导致内漏假阳性,在阳性识别后可以省略CEUS和CTA等资源密集型和侵入性更强的成像研究。