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免疫功能正常患者原发性皮肤奴卡菌病 1 例:病例报告及文献复习

A rare case of primary cutaneous Nocardia vinacea in an immunocompetent patient: A case report and a review of the literature.

机构信息

Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy.

Infectious Diseases Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.

出版信息

Diagn Microbiol Infect Dis. 2024 Jul;109(3):116307. doi: 10.1016/j.diagmicrobio.2024.116307. Epub 2024 Apr 16.

Abstract

The nocardiae are a complex group of bacteria belonging to the aerobic saprophytes actinomycetes. Although nocardiosis typically occurs in immunocompromised patients, infection may occasionally develop in immunocompetent patients as well. Here we describe a rare case of primary cutaneous nocardiosis due to Nocardia vinacea in an immunocompetent 79-year-old patient. Since cutaneous nocardiosis presents variably and mimics other cutaneous infections, acid-fast and Gram stainings on clinical samples are significant to obtain a rapid and presumptive diagnosis.

摘要

诺卡氏菌是一组属于需氧腐生菌放线菌的复杂细菌。尽管诺卡氏菌病通常发生在免疫功能低下的患者中,但感染也可能偶尔发生在免疫功能正常的患者中。在这里,我们描述了一例罕见的免疫功能正常的 79 岁患者由 Nocardia vinacea 引起的原发性皮肤诺卡氏菌病。由于皮肤诺卡氏菌病的表现各不相同,并模仿其他皮肤感染,因此临床样本的抗酸和革兰氏染色对于获得快速和初步诊断非常重要。

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