State Key Laboratory of Resource Insects, College of Sericulture, Textile and Biomass Sciences, Southwest University, Chongqing 400715, China.
Guangxi Key Laboratory of Sericultural Genetic Improvement and Efficient Breeding, Guangxi Zhuang Autonomous Region, Nanning 530007, China.
Bioresour Technol. 2024 Jun;402:130821. doi: 10.1016/j.biortech.2024.130821. Epub 2024 May 10.
Probiotics have attracted considerable attention in animal husbandry due to their positive effect on animal growth and health. This study aimed to screen candidate probiotic strain promoting the growth and health of silkworm and reveal the potential mechanisms. A novel probiotic Pediococcus pentosaceus strain (ZZ61) substantially promoted body weight gain, feed efficiency, and silk yield. These effects were likely mediated by changes in the intestinal digestive enzyme activity and nutrient provisioning (e.g., B vitamins) of the host, improving nutrient digestion and assimilation. Additionally, P. pentosaceus produced antimicrobial compounds and increased the antioxidant capacity to protect the host against pathogenic infection. Furthermore, P. pentosaceus affected the gut microbiome and altered the levels of gut metabolites (e.g., glycine and glycerophospholipids), which in turn promotes host nutrition and health. This study contributes to an improved understanding of the interactions between probiotic and host and promotes probiotic utilization in sericulture.
由于益生菌对动物生长和健康有积极影响，因此在畜牧业中受到了相当大的关注。本研究旨在筛选促进家蚕生长和健康的候选益生菌菌株，并揭示其潜在机制。一种新型益生菌戊糖片球菌（ZZ61）可显著促进蚕体增重、饲料效率和产丝量。这些效果可能是通过改变宿主的肠道消化酶活性和营养供应（例如 B 族维生素）来介导的，从而改善了营养物质的消化和吸收。此外，戊糖片球菌产生了抗菌化合物并提高了抗氧化能力，以保护宿主免受病原体感染。此外，戊糖片球菌还影响肠道微生物组并改变了肠道代谢物（例如甘氨酸和甘油磷脂）的水平，从而促进了宿主的营养和健康。本研究有助于更好地理解益生菌和宿主之间的相互作用，并促进了益生菌在家蚕养殖中的利用。
