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临床医生对眼眶疾病谱的处理方法:概述

Clinician's approach for spectrum of orbital diseases: An overview.

作者信息

Khan Lubna

机构信息

Department of Ophthalmology, All India Institute of Medical Sciences, Raipur, Chhattisgarh, India.

出版信息

J Family Med Prim Care. 2024 Mar;13(3):851-858. doi: 10.4103/jfmpc.jfmpc_761_23. Epub 2024 Apr 4.

Abstract

PURPOSE

To study the varied clinical presentation and outcome of management of orbital diseases and to ascertain the concordance of FNAC with histopathology.

MATERIALS AND METHODS

This is a prospective interventional study wherein each patient's clinical presentation was noted. Outcome of management was evaluated based on symptomatic relief, regression of signs, noting any intraoperative or postsurgical complication, recurrence, and cosmetic result in terms of surgical scar.

RESULTS

Neoplasia was commonest 33/76; (43.42%), followed by infective and inflammatory conditions 21/76; (27.63% cases), thyroid-associated orbitopathy accounting for 12/76 cases (15.78%), whereas cystic lesions and vascular malformations were 4/76 (5.26%) each. Other disorders constituted a mere 2.65%. Proptosis was the commonest mode of presentation. It was seen in seventy out of seventy-six patients (92.1%). In 86.3% of the cases, there was successful surgical outcome. Of 22 surgically managed cases, recurrence was noted in three cases (13.6%). 90% concordance was seen with histopathology in cases where FNAC was done prior to surgery for diagnosing nature of disease.

CONCLUSIONS

Majority of orbital and adnexal conditions can be provisionally diagnosed based on imaging; however, an adjunct invasive investigation such as FNAC or biopsy may be required. In the present study, in seven cases (9.2%) FNAC was needed, whereas in two cases (2.63%) biopsy was needed. A definitive diagnosis was confirmed by histopathology in 22 surgically managed cases and by excision biopsy in two. 22/76 (28.94%) of the cases needed surgical treatment, and other cases required conservative or palliative approach.

摘要

目的

研究眼眶疾病的不同临床表现及治疗结果,并确定细针穿刺抽吸活检(FNAC)与组织病理学结果的一致性。

材料与方法

这是一项前瞻性干预性研究,记录了每位患者的临床表现。根据症状缓解情况、体征消退情况、记录任何术中或术后并发症、复发情况以及手术瘢痕的美容效果来评估治疗结果。

结果

肿瘤是最常见的疾病,共33例/76例(43.42%),其次是感染性和炎症性疾病,共21例/76例(27.63%),甲状腺相关眼病占12例/76例(15.78%),而囊性病变和血管畸形各占4例/76例(5.26%)。其他疾病仅占2.65%。眼球突出是最常见的表现方式。76例患者中有70例出现眼球突出(92.1%)。86.3%的病例手术治疗成功。在22例接受手术治疗的病例中,有3例出现复发(13.6%)。在术前进行FNAC以诊断疾病性质的病例中,与组织病理学结果的一致性为90%。

结论

大多数眼眶及附属器疾病可根据影像学进行初步诊断;然而,可能需要辅助的侵入性检查,如FNAC或活检。在本研究中,7例(9.2%)需要进行FNAC,2例(2.63%)需要进行活检。22例接受手术治疗的病例经组织病理学确诊,2例经切除活检确诊。22/76(28.94%)的病例需要手术治疗,其他病例需要保守或姑息治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e82/11086771/a5d44969c47e/JFMPC-13-851-g001.jpg

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