Orbital Disease and Oculoplastic Surgery Dept., Tianjin International Joint Research and Development Centre of Ophthalmology and Vision Science, Eye Institute and School of Optometry, Tianjin Medical University Eye Hospital, Tianjin, China.
Department of Ophthalmology, Tianjin First Center Hospital, Tianjin, China.
Eye (Lond). 2021 Sep;35(9):2535-2542. doi: 10.1038/s41433-020-01270-7. Epub 2020 Nov 12.
This study aimed to evaluate the risk factors of postoperative severe vision impairment (PSVI) for a primary orbital tumour in the muscle cone.
A retrospective analysis of the patients who underwent orbitotomy for primary intraconal tumours at the Tianjin Medical University Eye Hospital from January 2010 to December 2015.
A total of 165 cases of orbitotomy for primary orbital tumours in the muscle cone were included in the study. Postoperatively, 12 cases with vision acuity ≤20/400 or ≥4 rows of vision decline and without any corrected effect were analysed as PSVI, including no light perception (NLP) for 3 cases. The multivariate logistic regression indicated that the tumour in orbital apex (P = 0.048, OR = 4.912, 95% CI: 1.011-23.866), severe optic nerve displacement (P = 0.030, OR = 6.007, 95% CI: 1.184-30.473) and intraoperative tight adhesion (P = 0.003, OR = 12.031, 95% CI: 2.282-63.441) were the independent risk factors for PSVI.
The incidence of PSVI for the intraconal tumour was 7.3%, and the incidence of NLP was 1.8%. The tumour in orbital apex, severe optic nerve displacement and intraoperative tight adhesion were independent risk factors for PSVI.
本研究旨在评估肌锥内原发性眼眶肿瘤术后严重视力损害（PSVI）的危险因素。
回顾性分析 2010 年 1 月至 2015 年 12 月在天津医科大学眼科医院行眶切开术治疗肌锥内原发性肿瘤的患者。
共纳入 165 例肌锥内原发性眼眶肿瘤眶切开术患者。术后视力视力 acuity≤20/400 或≥4 行视力下降且无任何矫正效果的 12 例患者被分析为 PSVI，其中 3 例无光感（NLP）。多因素 logistic 回归分析显示，眶尖肿瘤（P=0.048，OR=4.912，95%CI：1.011-23.866）、严重视神经移位（P=0.030，OR=6.007，95%CI：1.184-30.473）和术中紧密粘连（P=0.003，OR=12.031，95%CI：2.282-63.441）是 PSVI 的独立危险因素。
肌锥内肿瘤 PSVI 的发生率为 7.3%，NLP 的发生率为 1.8%。眶尖肿瘤、严重视神经移位和术中紧密粘连是 PSVI 的独立危险因素。
