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曲霉性腹膜炎:治疗、生存率及恢复腹膜透析情况

Aspergillus peritonitis: therapy, survival, and return to peritoneal dialysis.

作者信息

Miles A M, Barth R H

机构信息

Renal Division, Veterans Affairs Medical Center, Brooklyn, NY 11209, USA.

出版信息

Am J Kidney Dis. 1995 Jul;26(1):80-3. doi: 10.1016/0272-6386(95)90158-2.

DOI:10.1016/0272-6386(95)90158-2
PMID:7611273
Abstract

Peritonitis caused by fungi of the species Aspergillus is rare in peritoneal dialysis patients and is associated with high mortality. Four of the six reported survivors have been unable to resume peritoneal dialysis. We report the successful treatment of Aspergillus niger peritonitis with a combination of intravenous amphotericin B and peritoneal catheter removal in a patient on continuous ambulatory peritoneal dialysis (CAPD), and review previously reported cases of Aspergillus peritonitis. Our patient returned to CAPD after 2 months and has maintained good peritoneal transport 1 year after resumption of CAPD. The early recognition and aggressive treatment of peritonitis due to Aspergillus sp may allow eventual return to and successful maintenance of CAPD.

摘要

曲霉菌属真菌引起的腹膜炎在腹膜透析患者中较为罕见,且死亡率较高。已报道的6例幸存者中有4例无法恢复腹膜透析。我们报告了1例持续性非卧床腹膜透析(CAPD)患者,通过静脉注射两性霉素B联合拔除腹膜导管成功治疗了黑曲霉腹膜炎,并回顾了先前报道的曲霉菌腹膜炎病例。我们的患者在2个月后恢复了CAPD,恢复CAPD 1年后腹膜转运功能良好。对曲霉菌引起的腹膜炎进行早期识别和积极治疗,可能最终使患者恢复并成功维持CAPD。

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