Oskolkova S N
Zh Nevropatol Psikhiatr Im S S Korsakova. 1985;85(4):557-60.
The authors examined 82 patients suffering from reactive depressions with a relatively acute, subacute and protracted course, 10 patients with a reactive onset of schizophrenia and 24 normal subjects. The test subjects were examined over time for titres of heterohemolysins, S-RB, antibodies against cerebral antigens and the administered drugs as well as for relative parameters of T- and B-rosettes. The results obtained make it possible to identify the most frequent combinations of the examined parameters in the above groups of patients with various symptomatology. Immunological indices may be an important criterion for selecting the therapy of patients with reactive depressions. Thus the detection in the serum of antibodies against the administered drugs may serve as a sufficient basis for changing the therapy and using medicaments of a different chemical structure.
作者检查了82例患有反应性抑郁症的患者，其病程相对急性、亚急性和迁延性，10例反应性起病的精神分裂症患者以及24名正常受试者。对受试对象进行了一段时间的检查，检测其异嗜性溶血素、S-RB、抗脑抗原抗体和所用药物的滴度，以及T和B玫瑰花结的相关参数。所获得的结果使得识别上述具有各种症状学表现的患者组中所检查参数的最常见组合成为可能。免疫指标可能是选择反应性抑郁症患者治疗方法的重要标准。因此，血清中所用药的抗体检测结果可作为改变治疗方案并使用不同化学结构药物的充分依据。
