Uehara M
Acta Derm Venereol Suppl (Stockh). 1985;114:82-6. doi: 10.2340/000155551148286.
Of 200 atopic dermatitis patients observed during cold months, 44 (22%) had ichthyosis vulgaris. Histologically, the dry skin in atopic dermatitis coexistent with ichthyosis demonstrated ichthyotic features which were frequently superimposed with eczematous changes. The dry skin in pure atopic dermatitis demonstrated the histology of mild eczema. Examinations using monoclonal antibodies showed that the dry skin in pure atopic dermatitis had increased numbers of OKT6-positive cells in epidermis. The lymphocytes in the dermal infiltrates consisted predominantly of LEU-3a-positive cells. It is concluded that the dry skin often seen in atopic dermatitis may be a mild eczematous lesion of atopic dermatitis, or a manifestation of concomitant ichthyosis, or a complex of these two changes.
在寒冷季节观察的200例特应性皮炎患者中，44例（22%）患有寻常型鱼鳞病。组织学上，特应性皮炎合并鱼鳞病的干性皮肤表现出鱼鳞病特征，且常叠加有湿疹样改变。单纯特应性皮炎的干性皮肤表现为轻度湿疹的组织学特征。使用单克隆抗体检测显示，单纯特应性皮炎的干性皮肤表皮中OKT6阳性细胞数量增加。真皮浸润中的淋巴细胞主要由LEU-3a阳性细胞组成。结论是，特应性皮炎中常见的干性皮肤可能是特应性皮炎的轻度湿疹样病变，或合并鱼鳞病的表现，或这两种变化的复合体。
