Uehara M, Miyauchi H
Arch Dermatol. 1984 Sep;120(9):1186-90.
Uninvolved skin sites in 436 consecutive patients, 6 to 25 years old, with atopic dermatitis were observed during the winter months (from November to February). Ichthyosis vulgaris occurred in 133 patients. Of the 303 remaining patients, only 11 (4%) had generalized dry skin; 191 (63%) exhibited focal areas of dry skin; and 95 (33%) showed only normal-appearing skin. Microscopically, in 41 patients, dry skin associated with atopic dermatitis showed mild eczematous changes. Dry skin coexistent with ichthyosis in patients with atopic dermatitis revealed ichthyotic changes frequently superimposed on eczematous changes. We suggest that in patients with atopic dermatitis the presence of dry skin may reflect mild eczematous changes, a manifestation of concomitant ichthyosis, or a complex of both of these changes.
在冬季（11月至2月）观察了436例6至25岁的特应性皮炎患者未受累的皮肤部位。其中133例患有寻常型鱼鳞病。在其余303例患者中，只有11例（4%）有全身性皮肤干燥；191例（63%）有局部皮肤干燥区域；95例（33%）皮肤外观正常。显微镜下，41例特应性皮炎相关的皮肤干燥表现为轻度湿疹样改变。特应性皮炎患者中与鱼鳞病并存的皮肤干燥常表现为鱼鳞病样改变叠加在湿疹样改变之上。我们认为，在特应性皮炎患者中，皮肤干燥的存在可能反映轻度湿疹样改变、伴发鱼鳞病的表现或这两种改变的复合体。
