Michaud Amélie, Koskoletos Chris, Patterson Brooke E, Crossley Kay M, Birmingham Trevor B, Culvenor Adam G, Hart Harvi F
Action Sport Physio, Sherbrooke, Canada.
School of Physical Therapy, Western University, London, Canada.
Osteoarthr Cartil Open. 2024 Apr 25;6(2):100473. doi: 10.1016/j.ocarto.2024.100473. eCollection 2024 Jun.
To evaluate adiposity after anterior cruciate ligament reconstruction (ACLR): i) cross-sectionally (1-year post-ACLR) compared to uninjured controls; ii) longitudinally up to 5 years post-ACLR; and iii) associations with patient-reported symptoms and physical performance.
In 107 individuals post-ACLR and 19 controls, we assessed global (BMI), peripheral (subcutaneous adipose tissue thickness on the posteromedial side of knee MRI), and central (waist circumference in ACLR group) adiposity. Patient-reported symptoms (Knee injury and Osteoarthritis Outcome Score) and physical performance (hop for distance) were evaluated at 1 and 5 years post-ACLR. Linear regression models evaluated adiposity between groups. Paired t-tests evaluated changes in adiposity from 1- to 5 years post-ACLR. Linear regression models analyzed adiposity's associations with patient-reported symptoms and physical performance at 1-year post-ACLR, changes in symptoms and performance over 4 years post-ACLR, and longitudinal changes in adiposity and symptoms and performance, controlling for age, sex, and activity level.
Individuals 1-year post-ACLR were associated with higher average global (3 kg/m) and peripheral adiposity (2.3 mm). From 1- to 5 years post-ACLR, higher average global (0.58 kg/m) and central (5 cm) adiposity, and lower average peripheral adiposity (1.3 mm) were observed. In general, adiposity at one-year post-ACLR was negatively associated with patient-reported symptoms and physical performance, and changes from 1 to 5 years post-ACLR. Increases in adiposity were negatively associated with changes in patient-reported symptoms and physical performance over four years post-ACLR.
Greater global and central adiposity is a feature of young adults following ACLR and influences current and future patient-reported symptoms and physical performance.
评估前交叉韧带重建术（ACLR）后的肥胖情况：i）横断面研究（ACLR术后1年）与未受伤对照组进行比较；ii）纵向研究ACLR术后长达5年的情况；iii）与患者报告的症状及身体机能的关联。
对107例ACLR术后患者和19例对照组进行研究，我们评估了总体肥胖情况（BMI）、外周肥胖情况（膝关节MRI后内侧皮下脂肪组织厚度）和中心肥胖情况（ACLR组的腰围）。在ACLR术后1年和5年评估患者报告的症状（膝关节损伤和骨关节炎疗效评分）和身体机能（跳远）。线性回归模型评估组间肥胖情况。配对t检验评估ACLR术后1年至5年肥胖情况的变化。线性回归模型分析ACLR术后1年肥胖情况与患者报告的症状及身体机能的关联、ACLR术后4年症状和机能的变化以及肥胖情况、症状和机能的纵向变化，并对年龄、性别和活动水平进行控制。
ACLR术后1年的个体平均总体肥胖情况（3 kg/m²）和外周肥胖情况（2.3 mm）较高。ACLR术后1年至5年，观察到平均总体肥胖情况（0.58 kg/m²）和中心肥胖情况（5 cm）较高，而平均外周肥胖情况（1.3 mm）较低。一般来说，ACLR术后1年的肥胖情况与患者报告的症状及身体机能呈负相关，且与ACLR术后1年至5年的变化呈负相关。肥胖情况的增加与ACLR术后4年患者报告的症状及身体机能的变化呈负相关。
更大的总体和中心肥胖是ACLR术后年轻成年人的一个特征，并影响当前和未来患者报告的症状及身体机能。
