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正念对焦虑和抑郁症状的预期影响可能是虚假的:对元分析交叉滞后面板分析的模拟重新分析。

Prospective effects of mindfulness on anxiety and depressive symptoms may be spurious: Simulated reanalysis of a meta-analytic cross-lagged panel analysis.

机构信息

Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.

出版信息

PLoS One. 2024 May 13;19(5):e0302141. doi: 10.1371/journal.pone.0302141. eCollection 2024.

Abstract

A recent meta-analysis claimed decreasing prospective effects of acting with awareness and non-reacting, two facets of dispositional mindfulness, on subsequent anxiety and depressive symptoms. However, the meta-analytic cross-lagged effects were estimated while adjusting for a prior measurement of the outcome variable and it is known that such adjusted cross-lagged effects may be spurious due to correlations with residuals and regression to the mean. We fitted competing models on simulations of the same meta-analytic data and found that prospective effects of the mindfulness facets on anxiety and depressive symptoms probably were spurious. It is important for researchers to be aware of limitations of adjusted cross-lagged effects, meta-analytically estimated or not, in order not to overinterpret findings.

摘要

最近的一项荟萃分析声称,减少表现出的意识和非反应性的前瞻性影响,这两个方面的特质正念,对随后的焦虑和抑郁症状。然而,元分析交叉滞后效应是在调整结果变量的先前测量值的情况下估计的,并且已知由于与残差和向均值回归的相关性,这种调整后的交叉滞后效应可能是虚假的。我们在相同的荟萃分析数据的模拟中拟合了竞争模型,发现正念特征对焦虑和抑郁症状的前瞻性影响可能是虚假的。重要的是,研究人员要意识到调整后的交叉滞后效应的局限性,无论是元分析估计的还是其他的,以免过度解释研究结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afe3/11090347/612903f710e4/pone.0302141.g001.jpg

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