奥瑞他万星在耐甲氧西林金黄色葡萄球菌所致复发性骨感染患者中的应用及血药浓度监测 - Suppr

Oritavancin use in patients with recurrent bone infections by methicillin-resistant Staphylococcus aureus with monitoring of concentrations.

作者信息

Bongiovanni Marco, Thoueille Paul, Barda Beatrice, Mercier Thomas, Marzolini Catia, Ramponi Niccolò, Choong Eva, Cantù Marco, Decosterd Laurent A, Bernasconi Enos

机构信息

Division of Infectious Diseases, Ente Ospedaliero Cantonale, Lugano, Switzerland.

Division of Infectious Diseases and Hospital Epidermiology, University Hospital Basel, Basel, Switzerland.

出版信息

Eur J Clin Microbiol Infect Dis. 2024 Jul;43(7):1503-1504. doi: 10.1007/s10096-024-04844-5. Epub 2024 May 14.

DOI:10.1007/s10096-024-04844-5

PMID:38740656

Abstract

摘要

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Oritavancin use in patients with recurrent bone infections by methicillin-resistant Staphylococcus aureus with monitoring of concentrations.奥瑞他万星在耐甲氧西林金黄色葡萄球菌所致复发性骨感染患者中的应用及血药浓度监测

Eur J Clin Microbiol Infect Dis. 2024 Jul;43(7):1503-1504. doi: 10.1007/s10096-024-04844-5. Epub 2024 May 14.

Treatment of chronic osteomyelitis with multidose oritavancin: A case series and literature review.多剂量奥沙利万古霉素治疗慢性骨髓炎：病例系列和文献复习。

Int J Antimicrob Agents. 2019 Apr;53(4):429-434. doi: 10.1016/j.ijantimicag.2018.11.023. Epub 2018 Dec 8.

Efficacy of fosfomycin in experimental osteomyelitis due to methicillin-resistant Staphylococcus aureus.磷霉素治疗耐甲氧西林金黄色葡萄球菌所致实验性骨髓炎的疗效。

Antimicrob Agents Chemother. 2011 Feb;55(2):931-3. doi: 10.1128/AAC.00881-10. Epub 2010 Nov 22.

Variable daptomycin susceptibility in patients receiving intravenous vancomycin for meticillin-resistant Staphylococcus aureus infections.接受静脉注射万古霉素治疗耐甲氧西林金黄色葡萄球菌感染的患者中达托霉素敏感性的变化

Int J Antimicrob Agents. 2010 Mar;35(3):306-8. doi: 10.1016/j.ijantimicag.2009.10.022. Epub 2009 Dec 24.

Successful treatment of methicillin-resistant Staphylococcus aureus osteomyelitis with combination therapy using linezolid and rifampicin under therapeutic drug monitoring.在治疗药物监测下，使用利奈唑胺和利福平联合治疗耐甲氧西林金黄色葡萄球菌骨髓炎取得成功。

J Infect Chemother. 2016 May;22(5):331-4. doi: 10.1016/j.jiac.2015.11.012. Epub 2015 Dec 28.

Telavancin for the treatment of methicillin-resistant Staphylococcus aureus osteomyelitis.替考拉宁治疗耐甲氧西林金黄色葡萄球菌骨髓炎。

J Antimicrob Chemother. 2011 Nov;66(11):2675-7. doi: 10.1093/jac/dkr329. Epub 2011 Aug 10.

A stewardship program's retrospective evaluation of vancomycin AUC24/MIC and time to microbiological clearance in patients with methicillin-resistant Staphylococcus aureus bacteremia and osteomyelitis. stewardship 项目回顾性评估耐甲氧西林金黄色葡萄球菌菌血症和骨髓炎患者的万古霉素 AUC24/MIC 和微生物学清除时间。

Clin Ther. 2013 Jun;35(6):772-9. doi: 10.1016/j.clinthera.2013.05.008.

Pharmacodynamics of a simulated single 1,200-milligram dose of oritavancin in an in vitro pharmacokinetic/pharmacodynamic model of methicillin-resistant staphylococcus aureus infection.在耐甲氧西林金黄色葡萄球菌感染的体外药代动力学/药效学模型中，模拟单次 1200 毫克奥他万古霉素的药效动力学。

Antimicrob Agents Chemother. 2013 Jan;57(1):205-11. doi: 10.1128/AAC.01428-12. Epub 2012 Oct 22.

Antimicrobial options in the treatment of adult staphylococcal bone and joint infections in an era of drug shortages.药物短缺时代成人葡萄球菌性骨与关节感染的抗菌治疗选择

Orthopedics. 2012 May;35(5):401-7. doi: 10.3928/01477447-20120426-07.

In vivo assessment of the antimicrobial activity of a calcium-deficient apatite vancomycin drug delivery system in a methicillin-resistant Staphylococcus aureus rabbit osteomyelitis experimental model.在耐甲氧西林金黄色葡萄球菌兔骨髓炎实验模型中体内评估缺钙磷灰石万古霉素药物输送系统的抗菌活性。

Antimicrob Agents Chemother. 2010 Feb;54(2):950-2. doi: 10.1128/AAC.00434-09. Epub 2009 Nov 23.

引用本文的文献

Can Oritavancin Be Used for Treatment and/or Suppressive Antimicrobial Therapy of Bone and Joint Infections Caused by Vancomycin-resistant Enterococcus faecium?奥利万星可用于治疗和/或抑制耐万古霉素屎肠球菌引起的骨和关节感染吗？

Clin Orthop Relat Res. 2025 Mar 14;483(7):1225-33. doi: 10.1097/CORR.0000000000003449.

Long-Acting Antibiotics: New Opportunities Beyond Acute Bacterial Skin and Skin Structure Infections (ABSSSIs)!长效抗生素：急性细菌性皮肤及皮肤结构感染（ABSSSIs）之外的新机遇！

Antibiotics (Basel). 2025 Feb 7;14(2):164. doi: 10.3390/antibiotics14020164.

本文引用的文献

Role of Oritavancin in the Treatment of Infective Endocarditis, Catheter- or Device-Related Infections, Bloodstream Infections, and Bone and Prosthetic Joint Infections in Humans: Narrative Review and Possible Developments.奥利万星在人类感染性心内膜炎、导管或装置相关感染、血流感染以及骨和人工关节感染治疗中的作用：叙述性综述与可能的进展

Life (Basel). 2023 Apr 6;13(4):959. doi: 10.3390/life13040959.

Treatment of chronic osteomyelitis with multidose oritavancin: A case series and literature review.多剂量奥沙利万古霉素治疗慢性骨髓炎：病例系列和文献复习。

Int J Antimicrob Agents. 2019 Apr;53(4):429-434. doi: 10.1016/j.ijantimicag.2018.11.023. Epub 2018 Dec 8.

Single-dose oritavancin versus 7-10 days of vancomycin in the treatment of gram-positive acute bacterial skin and skin structure infections: the SOLO II noninferiority study.单剂奥塔万古霉素与 7-10 天万古霉素治疗革兰阳性急性细菌性皮肤和皮肤结构感染：SOLO II 非劣效性研究。

Clin Infect Dis. 2015 Jan 15;60(2):254-62. doi: 10.1093/cid/ciu778. Epub 2014 Oct 6.

Single-dose oritavancin in the treatment of acute bacterial skin infections.单剂量奥他万星治疗急性细菌性皮肤感染。

N Engl J Med. 2014 Jun 5;370(23):2180-90. doi: 10.1056/NEJMoa1310422.

Time-kill kinetics of oritavancin and comparator agents against Staphylococcus aureus, Enterococcus faecalis and Enterococcus faecium.奥利万星及对照药物对金黄色葡萄球菌、粪肠球菌和屎肠球菌的时间杀菌动力学

J Antimicrob Chemother. 2009 Jun;63(6):1191-9. doi: 10.1093/jac/dkp126. Epub 2009 Apr 15.

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Oritavancin use in patients with recurrent bone infections by methicillin-resistant Staphylococcus aureus with monitoring of concentrations.

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