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Single and chronic dose pharmacokinetic studies of sodium valproate in epileptic patients.

作者信息

Mihaly G W, Vajda F J, Miles J L, Louis W J

出版信息

Eur J Clin Pharmacol. 1979 Aug;16(1):23-9. doi: 10.1007/BF00644962.

DOI:10.1007/BF00644962
PMID:387418
Abstract
摘要

相似文献

1
Single and chronic dose pharmacokinetic studies of sodium valproate in epileptic patients.
Eur J Clin Pharmacol. 1979 Aug;16(1):23-9. doi: 10.1007/BF00644962.
2
Steady-state kinetics of valproic acid in epileptic patients.丙戊酸在癫痫患者中的稳态动力学
Clin Pharmacol Ther. 1978 Sep;24(3):324-32. doi: 10.1002/cpt1978243324.
3
Comparison of sodium valproate and phenytoin as single drug treatment in epilepsy.丙戊酸钠与苯妥英钠作为癫痫单药治疗的比较。
Epilepsia. 1981 Feb;22(1):27-33. doi: 10.1111/j.1528-1157.1981.tb04330.x.
4
Sodium valproate: pharmacokinetics and effectivensss in treating intractable seizures.丙戊酸钠：治疗难治性癫痫的药代动力学及有效性
Neurology. 1980 Jan;30(1):1-6. doi: 10.1212/wnl.30.1.1.
5
Steady-state valproate pharmacokinetics during long term therapy.
Clin Exp Neurol. 1983;19:183-91.
6
Epileptic seizures caused by low valproic acid levels from an interaction with meropenem.美罗培南相互作用导致丙戊酸水平降低引起的癫痫发作。
J Clin Pharm Ther. 2006 Aug;31(4):393-6. doi: 10.1111/j.1365-2710.2006.00743.x.
7
Sodium valproate (Epilim) in the treatment of refractory epilepsy.
N Z Med J. 1978 Jan 11;87(603):9-12.
8
Clinical implications of serum protein binding in epileptic children during sodium valproate maintenance therapy.丙戊酸钠维持治疗期间癫痫患儿血清蛋白结合的临床意义
Ther Drug Monit. 1984;6(4):414-23. doi: 10.1097/00007691-198412000-00006.
9
Rectal administration of sodium valproate in children.
Ital J Neurol Sci. 1984 Jun;5(2):189-93. doi: 10.1007/BF02043222.
10
Plasma sodium valproate levels and clinical response in epilepsy.癫痫患者的血浆丙戊酸钠水平与临床反应
Clin Exp Neurol. 1977;14:208-15.

引用本文的文献

1
Pharmacokinetic interactions between antiepileptic drugs. Clinical considerations.抗癫痫药物之间的药代动力学相互作用。临床考量。
Clin Pharmacokinet. 1996 Dec;31(6):470-93. doi: 10.2165/00003088-199631060-00005.
2
Clinically significant pharmacokinetic drug interactions with carbamazepine. An update.卡马西平具有临床意义的药代动力学药物相互作用。最新进展。
Clin Pharmacokinet. 1996 Sep;31(3):198-214. doi: 10.2165/00003088-199631030-00004.
3
Pharmacokinetic interactions with antiepileptic drugs.与抗癫痫药物的药代动力学相互作用。

本文引用的文献

1
[Pharmacodynamic properties of N-dipropylacetic acid].[N-二丙基乙酸的药效学特性]
Therapie. 1963 Mar-Apr;18:435-8.
2
Clinical trials of anti-epileptic drugs.抗癫痫药物的临床试验。
Psychiatr Neurol Neurochir. 1971 Mar-Apr;74(2):141-51.
3
Concentration of dipropylacetate in plasma.
Epilepsia. 1975 Nov;16(4):609-15. doi: 10.1111/j.1528-1157.1975.tb04743.x.
Clin Pharmacokinet. 1982 Jan-Feb;7(1):57-84. doi: 10.2165/00003088-198207010-00004.
4
Application of stable labelled drugs in clinical pharmacokinetic investigations.稳定标记药物在临床药代动力学研究中的应用。
Clin Pharmacokinet. 1982 Nov-Dec;7(6):490-507. doi: 10.2165/00003088-198207060-00002.
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Drug interactions with valproic acid.丙戊酸的药物相互作用
Drugs. 1982 Dec;24(6):543-56. doi: 10.2165/00003495-198224060-00004.
6
Valproic acid disposition in epileptic patients during combined antiepileptic maintenance therapy.癫痫患者在联合抗癫痫维持治疗期间丙戊酸的处置情况。
Eur J Clin Pharmacol. 1981;19(5):383-5. doi: 10.1007/BF00544590.
7
Plasma concentrations of valproate during maintenance therapy in epileptic children.
J Neurol. 1982;228(2):133-41. doi: 10.1007/BF00313758.
8
Effect of cimetidine and ranitidine on carbamazepine and sodium valproate pharmacokinetics.西咪替丁和雷尼替丁对卡马西平和丙戊酸钠药代动力学的影响。
Eur J Clin Pharmacol. 1984;27(3):341-3. doi: 10.1007/BF00542172.
9
Clinical pharmacokinetics of valproic acid--1988.丙戊酸的临床药代动力学——1988年
Clin Pharmacokinet. 1988 Dec;15(6):367-89. doi: 10.2165/00003088-198815060-00002.
10
Pharmacokinetic drug interactions with phenytoin (Part II).苯妥英的药代动力学药物相互作用（第二部分）。
Clin Pharmacokinet. 1990 Feb;18(2):131-50. doi: 10.2165/00003088-199018020-00004.
4
Controlled trial of sodium valproate in severe epilepsy.丙戊酸钠治疗严重癫痫的对照试验。
Br Med J. 1975 Nov 1;4(5991):255-6. doi: 10.1136/bmj.4.5991.255.
5
Sodium di-N-propylacetate (DPA) in the treatment of epilepsy. A review.二正丙基乙酸钠（DPA）治疗癫痫：综述
Epilepsia. 1975 Nov;16(4):549-73. doi: 10.1111/j.1528-1157.1975.tb04738.x.
6
Sodium valproate: a review of its pharmacological properties and therapeutic efficacy in epilepsy.丙戊酸钠：其药理学特性及在癫痫治疗中的疗效综述
Drugs. 1977 Feb;13(2):81-123. doi: 10.2165/00003495-197713020-00001.
7
Sodium valproate: dose-plasma level relationships and interdose fluctuations.
Clin Exp Neurol. 1978;15:145-53.
8
Plasma protein binding interaction between phenytoin and valproic acid in vitro.苯妥英与丙戊酸在体外的血浆蛋白结合相互作用。
Br J Clin Pharmacol. 1978 Dec;6(6):487-92. doi: 10.1111/j.1365-2125.1978.tb00871.x.
9
Disposition of sodium valproate in epileptic patients.丙戊酸钠在癫痫患者体内的处置情况。
Br J Clin Pharmacol. 1978 Jun;5(6):495-9. doi: 10.1111/j.1365-2125.1978.tb01663.x.
10
Gas chromatographic measurement of plasma levels of sodium valproate: tentative therapeutic range of a new anticonvulsant in the treatment of refractory epileptics.气相色谱法测定丙戊酸钠的血浆水平：一种新型抗惊厥药物治疗难治性癫痫患者的初步治疗范围
Clin Exp Pharmacol Physiol. 1978 Jan-Feb;5(1):67-73. doi: 10.1111/j.1440-1681.1978.tb00653.x.