Paquet K J
J Pediatr Surg. 1985 Apr;20(2):109-12. doi: 10.1016/s0022-3468(85)80280-3.
Esophageal varices in 59 consecutive children with portal hypertension were treated by paravariceal injection sclerotherapy. Repeated injections were performed using a special rigid instrument under general anesthesia. In children older than 10 a flexible endoscope was used without general anesthesia. Using 0.5% Polidocanol, a fibrous layer protecting varices against the further bleeding was produced in 59 children. Complications during treatment included hemorrhage, esophageal ulceration and stricture, each in two children. 55 children have been followed for 6 months to 10 years after two phases of paravariceal injection following the first phase of treatment. Three rebleeds have occurred in this group. Sclerotherapy was repeated. Thereafter, using a regular endoscopic control every year, no rebleeding occurred. Four children with liver cirrhosis died of liver failure. All other children except four foreign ones could be followed. 51 of them (86%) are alive.
对59例连续性门静脉高压患儿的食管静脉曲张采用曲张静脉旁注射硬化疗法进行治疗。在全身麻醉下使用一种特殊的硬质器械进行重复注射。对于10岁以上的儿童,在无全身麻醉的情况下使用可弯曲内镜。使用0.5%的聚多卡醇,在59例患儿中形成了一层保护曲张静脉防止进一步出血的纤维层。治疗期间的并发症包括出血、食管溃疡和狭窄,各有2例患儿出现。55例患儿在第一阶段治疗后进行了两期曲张静脉旁注射,之后随访了6个月至10年。该组发生了3次再出血。重复进行了硬化疗法。此后,每年进行常规内镜检查,未再发生出血。4例肝硬化患儿死于肝功能衰竭。除4例外国患儿外,所有其他患儿均能进行随访。其中51例(86%)存活。