[儿童急慢性支气管肺部疾病的病因学。II. 采用对流免疫电泳、补体结合及被动血凝反应对特异性免疫反应的研究]

[Etiology of acute and chronic bronchopulmonary diseases in children. II. A study of the specific immune response by counterimmunoelectrophoresis and the complement fixation and passive hemagglutination reactions].

作者信息

Katosova L K, Sattarov G N, Chynyeva D K, Naĭmushina N B, Kaverina K G

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1985 Apr(4):11-5.

Abstract

Specific immune response to Streptococcus pneumoniae and Haemophilus influenzae has been studied in 158 children with acute pneumonia and pleuritis and 128 children with chronic pneumonia by countercurrent immunoelectrophoresis (CIE) and in the complement fixation (CFT) and passive hemagglutination (PHA) tests. The use of CIE leads to the detection of antibodies to H. influenzae in 23.7% of children with acute pneumonia and in 46.9% of children with chronic pneumonia. In the CFT antibodies to H. influenzae are also more often detected in children with chronic pneumonia (48%) than in those with acute respiratory infections (12.2%). In the PHA test high titers of antibodies to type b H. influenzae capsular polysaccharide occur in 11.9% of children with acute pneumonia and in 8.2% of children with chronic pneumonia.

摘要

通过对流免疫电泳（CIE）、补体结合试验（CFT）和被动血凝试验（PHA），对158例急性肺炎和胸膜炎患儿以及128例慢性肺炎患儿针对肺炎链球菌和流感嗜血杆菌的特异性免疫反应进行了研究。采用CIE检测发现，23.7%的急性肺炎患儿和46.9%的慢性肺炎患儿体内存在抗流感嗜血杆菌抗体。在CFT中，慢性肺炎患儿（48%）比急性呼吸道感染患儿（12.2%）更常检测到抗流感嗜血杆菌抗体。在PHA试验中，11.9%的急性肺炎患儿和8.2%的慢性肺炎患儿体内出现高滴度的抗b型流感嗜血杆菌荚膜多糖抗体。