Rao S M, Glatt S, Hammeke T A, McQuillen M P, Khatri B O, Rhodes A M, Pollard S
Arch Neurol. 1985 Jul;42(7):678-82. doi: 10.1001/archneur.1985.04060070068018.
Forty-seven patients with chronic progressive multiple sclerosis were examined to assess the possible relationship between cerebral atrophy (by computed tomography [CT] ) and performance on neuropsychological tests of memory and verbal intelligence. Nineteen patients were found to have mildly dilated ventricles and another nine patients had moderate to severe ventricular enlargement. Performance on memory and intelligence testing was related to the degree of ventriculomegaly. Three linear CT measurements were also recorded. Using this method, the width of the third ventricle proved to be the best indicator of intellectual and memory dysfunction. Measures of cognition and ventricular size did not correlate with length of illness or overall disability as rated by the Kurtzke Disability Status Score.
对47例慢性进行性多发性硬化症患者进行了检查，以评估脑萎缩（通过计算机断层扫描[CT]）与记忆和语言智力神经心理学测试表现之间的可能关系。发现19例患者脑室轻度扩张，另外9例患者有中度至重度脑室扩大。记忆和智力测试的表现与脑室扩大程度有关。还记录了三项CT线性测量值。使用这种方法，第三脑室宽度被证明是智力和记忆功能障碍的最佳指标。认知测量和脑室大小与疾病持续时间或库茨克残疾状态评分所评定的总体残疾程度无关。
