Opt Lett. 2024 May 15;49(10):2729-2732. doi: 10.1364/OL.514077.
In recent years, the emergence of a variety of novel optical microscopy techniques has enabled the generation of virtual optical stains of unlabeled tissue specimens, which have the potential to transform existing clinical histopathology workflows. In this work, we present a simultaneous deep ultraviolet transmission and scattering microscopy system that can produce virtual histology images that show concordance to conventional gold-standard histological processing techniques. The results of this work demonstrate the system's diagnostic potential for characterizing unlabeled thin tissue sections and streamlining histological workflows.
近年来，各种新型的光学显微镜技术的出现使得对未标记的组织标本进行虚拟光学染色成为可能，这有可能改变现有的临床组织病理学工作流程。在这项工作中，我们提出了一种同时进行深紫外透射和散射显微镜系统，该系统可以产生与传统金标准组织处理技术一致的虚拟组织学图像。这项工作的结果表明了该系统对未标记的薄组织切片进行特征描述和简化组织学工作流程的诊断潜力。
