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基于聚合物的级联波导布拉格光栅用于血糖传感。

Polymer-based cascaded waveguide Bragg grating for blood glucose sensing.

出版信息

Opt Lett. 2024 May 15;49(10):2821-2824. doi: 10.1364/OL.523504.

DOI:10.1364/OL.523504
PMID:38748170
Abstract

Waveguide Bragg grating (WBG) blood glucose sensing, as a biological sensing technology with broad application prospects, plays an important role in the fields of health management and medical treatment. In this work, a polymer-based cascaded WBG is applied to glucose detection. We investigated photonic devices with two different grating structures cascaded-a crossed grating and a bilateral grating-and analyzed the effects of the crossed grating period, bilateral grating period, and number of grating periods on the sensing performance of the glucose sensor. Finally, the spectral reflectance characteristics, response time, and sensing specificity of the cascaded WBG were evaluated. The experimental results showed that the glucose sensor has a sensitivity of 175 nm/RIU in a glucose concentration range of 0-2 mg/ml and has the advantages of high integration, a narrow bandwidth, and low cost.

摘要

波导布拉格光栅(WBG)血糖传感作为一种具有广阔应用前景的生物传感技术,在健康管理和医疗领域发挥着重要作用。在这项工作中,我们应用基于聚合物的级联 WBG 进行葡萄糖检测。我们研究了具有两种不同光栅结构级联的光子器件——交叉光栅和双边光栅,并分析了交叉光栅周期、双边光栅周期和光栅周期数对葡萄糖传感器传感性能的影响。最后,评估了级联 WBG 的光谱反射率特性、响应时间和传感特异性。实验结果表明,该葡萄糖传感器在 0-2mg/ml 的葡萄糖浓度范围内具有 175nm/RIU 的灵敏度,具有高集成度、窄带宽和低成本的优点。

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