Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.
Newcastle University Centre for Cancer, Newcastle University, Newcastle upon Tyne, United Kingdom.
PLoS One. 2024 May 15;19(5):e0299321. doi: 10.1371/journal.pone.0299321. eCollection 2024.
Childhood, adolescent and young adult (CAYA) cancer survivors are vulnerable to adverse late-effects. For CAYA cancer survivors, tobacco smoking is the most important preventable cause of ill-health and early death. Yet, effective strategies to support smoking cessation in this group are lacking. The PRISM study aims to undertake multi-method formative research to explore the need for, and if appropriate, inform the future development of an evidence-based and theory-informed tobacco smoking cessation intervention for CAYA cancer survivors.
PRISM involves three phases of: 1) an environmental scan using multiple strategies to identify and examine a) smoking cessation interventions for CAYA cancer survivors that are published in the international literature and b) current smoking cessation services in England that may be available to, or tailorable to, CAYA cancer survivors; 2) a qualitative study involving semi-structured interviews with CAYA cancer survivors (aged 16-29 years and who are current or recent ex-smokers and/or current vapers) to explore their views and experiences of smoking, smoking cessation and vaping; and 3) stakeholder workshops with survivors, healthcare professionals and other stakeholders to consider the potential for a smoking cessation intervention for CAYA cancer survivors and what such an intervention would need to target and change. Findings will be disseminated to patient groups, healthcare professionals and researchers, through conference presentations, journal papers, plain English summaries and social media.
PRISM will explore current delivery of, perceived need for, and barriers and facilitators to, smoking cessation advice and support to CAYA cancer survivors from the perspective of both survivors and healthcare professionals. A key strength of PRISM is the user involvement throughout the study and the additional exploration of survivors' views on vaping, a behaviour which often co-occurs with smoking. PRISM is the first step in the development of a person-centred, evidence- and theory-based smoking cessation intervention for CAYA cancer survivors who smoke, which if effective, will reduce morbidity and mortality in the CAYA cancer survivor population.
儿童、青少年和青年期（CAYA）癌症幸存者易发生不良的晚期效应。对于 CAYA 癌症幸存者而言，吸烟是导致健康不良和早逝的最重要的可预防原因。然而，针对这一群体的有效戒烟策略却很缺乏。PRISM 研究旨在进行多方法形成性研究，以探索是否需要为 CAYA 癌症幸存者制定一种基于证据和理论的戒烟干预措施，如果需要，应如何制定。
PRISM 研究包含三个阶段：1）采用多种策略进行环境扫描，以识别和检查 a）国际文献中发表的针对 CAYA 癌症幸存者的戒烟干预措施，以及 b）英国当前可能适用于或可针对 CAYA 癌症幸存者进行调整的戒烟服务；2）一项涉及 CAYA 癌症幸存者（年龄在 16-29 岁之间，且目前或最近为戒烟者和/或当前为电子烟使用者）的半结构化访谈的定性研究，以探讨他们对吸烟、戒烟和使用电子烟的看法和经验；3）幸存者、医疗保健专业人员和其他利益相关者的利益相关者研讨会，以探讨针对 CAYA 癌症幸存者的戒烟干预措施的潜力，以及该干预措施需要针对和改变的方面。研究结果将通过会议演讲、期刊论文、通俗易懂的摘要和社交媒体向患者群体、医疗保健专业人员和研究人员进行传播。
PRISM 将从幸存者和医疗保健专业人员的角度探讨当前为 CAYA 癌症幸存者提供的戒烟建议和支持的提供情况、感知需求、障碍和促进因素。PRISM 的一个主要优势是在整个研究过程中都有患者参与，并且还探讨了幸存者对电子烟的看法，电子烟是一种经常与吸烟同时发生的行为。PRISM 是为吸烟的 CAYA 癌症幸存者制定以患者为中心、基于证据和理论的戒烟干预措施的第一步，如果有效，将降低 CAYA 癌症幸存者人群的发病率和死亡率。
