Tigani Domenico, Ferranti Calderoni Enrico, Melucci Giuseppe, Pizzo Alex, Ghilotti Margherita, Castelli Alberto, Pasta Gianluigi, Grassi Federico, Jannelli Eugenio
Department of Orthopaedic Surgery, Ospedale Maggiore C.A. Pizzardi, Largo B. Nigrisoli 2, 40133, Bologna, Italy.
Casa di cura Humanitas San Pio X Milano.
Orthop Rev (Pavia). 2024 May 13;16:117203. doi: 10.52965/001c.117203. eCollection 2024.
INTRODUCTION The incidence of periprosthetic fractures (PFFs) is estimated to range from 0.1% to 4.1%1, due to the increasing prevalence of joint arthroplasties, coupled with an aging population. Numerous risk factors, including advanced age (>80 years), female gender, implant type, prior diagnoses of osteonecrosis and rheumatoid arthritis, revision surgery, aseptic stem mobilization, and the use of non-cemented stems, have been identified. Survivors of periprosthetic fractures often experience functional deterioration, facing a fourfold higher risk of hospitalization for postoperative complications compared to patients undergoing primary implantation, especially in the first postoperative year. MATERIALS AND METHODS Between 2018 and 2022, at the Maggiore Hospitals in Bologna and the San Matteo Policlinic in Pavia, we performed osteosynthesis on 84 patients with periprosthetic fractures of Vancouver type B1 or C. In 38 patients, we employed angular stable plates with the Zimmer Biomet NCB-PP® system. In 46 patients, we utilized INTRAUMA plates: DF distal femur and PFF proximal. Relevant postoperative follow-up outcomes considered included reintervention, infectious complications, radiographic healing, and functional recovery, with reference to changes in the Glasgow Outcome Scale (GOS) and the Harris Hip Score (HHS). All patients underwent clinical and radiographic evaluations during the follow-up period, averaging 28 months (range: 12-48 months), with a minimum follow-up duration of 12 months. RESULTS At the 4-month postoperative assessment, 71% of patients maintained their preoperative functional level, 19% experienced a 1-point GOS scale drop, and 10% died (GOS 5). The average HHS at 4 months was 80.2 points (range: 65-90). At the 6-month follow-up, 98.2% of patients achieved complete healing on radiographic examination. Only 1 patient (1.2%) developed a pseudoarthrosis site with synthesis device rupture. Only 1 patient (1.2%) required additional surgical treatment 2 years later due to the development of un aseptic perisynthetic fluid collection, while the remaining 5 patients (6%) who developed complications benefited from conservative treatment: 4 patients (3.6%) with infectious complications were treated with intravenous antibiotics. In the 2 patients (2.3%) with mobilization or rupture of synthesis devices, clinical and radiographic monitoring was opted for. 8 patients (10.7%) died: one 48 hours after the surgery, and the other 7 more than one month after the surgery. CONCLUSION Our clinical findings align with to existing scientific literature on periprosthetic fractures (B1 and C according to Vancouver classification). Moreover, good stability has been guaranteed at the radiological follow up by Zimmer Biomet NCB-PP® and INTRAUMA DF distal femur and PFF proximal plates. The locking construct allows for improved stability especially in osteoporotic bone.
引言 由于关节置换术的日益普及以及人口老龄化,人工关节周围骨折(PFFs)的发生率估计在0.1%至4.1%之间。已确定了许多风险因素,包括高龄(>80岁)、女性、植入物类型、既往骨坏死和类风湿关节炎诊断、翻修手术、无菌性假体柄松动以及使用非骨水泥型假体柄。人工关节周围骨折的幸存者常出现功能恶化,与初次植入患者相比,术后并发症住院风险高出四倍,尤其是在术后第一年。
材料与方法 2018年至2022年期间,在博洛尼亚的马焦雷医院和帕维亚的圣马泰奥综合医院,我们对84例温哥华B1型或C型人工关节周围骨折患者进行了骨固定术。在38例患者中,我们使用了Zimmer Biomet NCB-PP®系统的角度稳定钢板。在46例患者中,我们使用了INTRAUMA钢板:DF股骨远端和PFF近端。考虑的相关术后随访结果包括再次干预、感染性并发症、影像学愈合和功能恢复,并参考格拉斯哥预后量表(GOS)和哈里斯髋关节评分(HHS)的变化。所有患者在随访期间均接受了临床和影像学评估,平均随访28个月(范围:12 - 48个月),最短随访时间为12个月。
结果 在术后4个月的评估中,71%的患者维持了术前功能水平,19%的患者GOS量表下降1分,10%的患者死亡(GOS 5)。4个月时的平均HHS为80.2分(范围:65 - 90)。在6个月的随访中,98.2%的患者在影像学检查中实现了完全愈合。只有1例患者(1.2%)出现了假关节部位且合成装置破裂。只有1例患者(1.2%)在2年后因无菌性合成周围积液的出现需要额外的手术治疗,而其余5例(6%)出现并发症的患者受益于保守治疗:4例(3.6%)感染性并发症患者接受了静脉抗生素治疗。在2例(2.3%)合成装置松动或破裂的患者中,选择了临床和影像学监测。8例患者(10.7%)死亡:1例在术后48小时死亡,另1例在术后1个月以上死亡。
结论 我们的临床研究结果与关于人工关节周围骨折(根据温哥华分类为B1和C型)的现有科学文献一致。此外,Zimmer Biomet NCB-PP®以及INTRAUMA DF股骨远端和PFF近端钢板在放射学随访中保证了良好的稳定性。锁定结构尤其在骨质疏松性骨中可提高稳定性。