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优化患者预后:多模式超前镇痛在电视辅助胸腔镜肺叶切除术中的影响

Optimizing patient outcomes: the impact of multimodal preemptive analgesia in video-assisted thoracoscopic lobectomy.

作者信息

Li Bing, Chen Yu, Ma Rong

机构信息

Department of Anesthesiology, Jiangsu Province Hospital and First Affiliated Hospital with Nanjing Medical University, Nanjing City, China.

出版信息

Interdiscip Cardiovasc Thorac Surg. 2024 May 2;38(5). doi: 10.1093/icvts/ivae096.

Abstract

OBJECTIVES

The aim of this study was to evaluate the efficacy of a multimodal preemptive analgesia management approach, specifically incorporating ultrasound-guided thoracic paravertebral block (UG-TPVB) in conjunction with intravenous analgesia, after video-assisted thoracoscopic (VATS) lobectomy under the guidance of enhanced recovery after surgery.

METHODS

A total of 690 patients who underwent VATS lobectomy between October 2021 and March 2022 were divided into the UG-TPVB group (group T, n = 345) and the control group (group C, n = 345). Patients in group T received UG-TPVB prior to the induction of general anaesthesia, while group C did not undergo nerve block. A comparison was conducted between the 2 groups regarding various indicators, including postoperative sedation, static/dynamic numeric rating scale scores, intraoperative fentanyl consumption, duration of mechanical ventilation/anaesthesia recovery/hospitalization, postoperative complications and other relevant factors.

RESULTS

The static/dynamic numeric rating scale scores of group T were lower than those of group C after surgery. Intraoperative fentanyl consumption in group T (0.384 ± 0.095 mg) was lower than that in group C (0.465 ± 0.053 mg). The duration of mechanical ventilation, anaesthesia recovery and hospitalization were significantly shorter in group T compared to group C. Patient satisfaction rate in group T (70.1%) was higher than that in group C (53.6%). All differences were statistically significant (P < 0.05).

CONCLUSIONS

The multimodal preemptive analgesia management strategy effectively reduces postoperative pain, decreases opioid consumption and promotes faster recovery in patients undergoing VATS lobectomy.

摘要

目的

本研究旨在评估一种多模式超前镇痛管理方法的疗效,特别是在术后加速康复指导下,将超声引导下胸椎旁神经阻滞(UG-TPVB)与静脉镇痛相结合,应用于电视辅助胸腔镜(VATS)肺叶切除术后。

方法

将2021年10月至2022年3月期间接受VATS肺叶切除术的690例患者分为UG-TPVB组(T组,n = 345)和对照组(C组,n = 345)。T组患者在全身麻醉诱导前接受UG-TPVB,而C组未进行神经阻滞。比较两组在术后镇静、静态/动态数字评分量表得分、术中芬太尼用量、机械通气/麻醉恢复/住院时间、术后并发症及其他相关因素等各项指标。

结果

术后T组的静态/动态数字评分量表得分低于C组。T组术中芬太尼用量(0.384±0.095mg)低于C组(0.465±0.053mg)。与C组相比,T组的机械通气、麻醉恢复和住院时间明显缩短。T组患者满意度(70.1%)高于C组(53.6%)。所有差异均有统计学意义(P < 0.05)。

结论

多模式超前镇痛管理策略可有效减轻VATS肺叶切除术后患者的疼痛,减少阿片类药物用量,并促进患者更快康复。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c684/11132815/82d2c4a5822b/ivae096f3.jpg

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