Kirklin J K, Blackstone E H, Zorn G L, Pacifico A D, Kirklin J W, Karp R B, Rogers W J
Circulation. 1985 Sep;72(3 Pt 2):II175-8.
To assess the intermediate-term results of emergency coronary revascularization for acute myocardial infarction, we analyzed all patients (n = 35) who underwent coronary artery bypass grafting within 48 hr of acute myocardial infarction between January 1, 1982, and March 1, 1983. All patients had complete revascularization of infarct and noninfarct areas (3.4 +/- 1.65 distal anastomoses per patient). All patients have been traced as of February 21, 1984. Median duration of follow-up was 17.4 months (range 11.2 to 23.7). One in-hospital death (2.9%, 70% confidence limits 0% to 9%) occurred with low cardiac output, and no deaths occurred in the four patients who were in cardiogenic shock before surgery. One late death occurred from cancer, and 1 year overall actuarial survival is 94%. One patient underwent successful cardiac transplantation 8 months after operation. Ninety-seven percent of surviving patients are in NYHA class I or II, and 82% (27/33) have had no postoperative angina; six patients have mild angina. No patient has suffered a subsequent myocardial infarction. The early and intermediate results support continued application of emergency revascularization in higher-risk subsets of patients with acute myocardial infarction.
为评估急性心肌梗死紧急冠状动脉血运重建的中期结果,我们分析了1982年1月1日至1983年3月1日期间在急性心肌梗死48小时内行冠状动脉旁路移植术的所有患者(n = 35)。所有患者梗死和非梗死区域均实现完全血运重建(每位患者平均有3.4±1.65个远端吻合口)。截至1984年2月21日,所有患者均已接受随访。随访时间中位数为17.4个月(范围11.2至23.7个月)。1例患者因心输出量低在住院期间死亡(2.9%,70%置信区间0%至9%),术前处于心源性休克的4例患者无死亡发生。1例患者死于癌症,1年总精算生存率为94%。1例患者术后8个月成功接受心脏移植。97%的存活患者心功能分级为纽约心脏协会(NYHA)I级或II级,82%(27/33)的患者术后无心绞痛;6例患者有轻度心绞痛。无患者发生后续心肌梗死。早期和中期结果支持在急性心肌梗死高危亚组患者中继续应用紧急血运重建。