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急诊冠状动脉旁路移植术的临床结果

Clinical outcome of urgent coronary artery bypass grafting.

作者信息

Kim Do-Kyun, Yoo Kyung-Jong, Hong You Sun, Chang Byung-Chul, Kang Meyun-Shick

机构信息

Department of Thoracic and Cardiovascular Surgery, Severance Hospital Cardiovascular Center, 134 Sinchon-dong, Seodaemun-gu, Seoul, Korea.

出版信息

J Korean Med Sci. 2007 Apr;22(2):270-6. doi: 10.3346/jkms.2007.22.2.270.

Abstract

Urgent coronary artery bypass grafting (CABG) has a higher mortality rate than elective CABG. The purpose of this study was to evaluate the clinical outcome of urgent CABG. From July 1992 to May 2005, 104 patients underwent urgent CABG. All patients required an urgent surgical revascularization within 24 hr of diagnostic coronary angiography. In-hospital mortality after urgent CABG was 17.3% (18/104). We compared preoperative characteristics and postoperative clinical outcomes between the survival group (n=86) and the mortality group (n=18). The mean age was 61.7 yr (range, 35-83). The most common cause of mortality was low cardiac output. The independent preoperative risk factors of mortality included advanced age (>70 yr) (OR=3.998, p=0.046), preoperative shock status (OR=6.542, p=0.011), and low ejection fraction (<40%) (OR=4.492, p=0.034). Other risk factors of mortality included prolonged cardiopulmonary bypass time, prolonged ventilator use, and extended intensive care unit stay. The 10-yr actuarial survival rate was 61%. Although the operative mortality rate was high after urgent CABG, a favorable long-term clinical outcome can be expected if the patients survive.

摘要

急诊冠状动脉旁路移植术(CABG)的死亡率高于择期CABG。本研究的目的是评估急诊CABG的临床结局。1992年7月至2005年5月,104例患者接受了急诊CABG。所有患者在诊断性冠状动脉造影后24小时内均需要进行紧急手术血运重建。急诊CABG后的院内死亡率为17.3%(18/104)。我们比较了生存组(n=86)和死亡组(n=18)的术前特征和术后临床结局。平均年龄为61.7岁(范围35 - 83岁)。最常见的死亡原因是心输出量低。死亡的独立术前危险因素包括高龄(>70岁)(OR=3.998,p=0.046)、术前休克状态(OR=6.542,p=0.011)和低射血分数(<40%)(OR=4.492,p=0.034)。其他死亡危险因素包括体外循环时间延长、呼吸机使用时间延长和重症监护病房停留时间延长。10年精算生存率为61%。尽管急诊CABG后的手术死亡率很高,但如果患者存活,可以预期有良好的长期临床结局。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/46bb/2693594/c4d6b1c09d4d/jkms-22-270-g001.jpg

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