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全球 1990-2019 年矽肺的发病率、死亡率和伤残调整生命年:来自 2019 年全球疾病负担研究的证据。

Incidence, mortality, and disability-adjusted life years due to silicosis worldwide, 1990-2019: evidence from the global burden of disease study 2019.

机构信息

Department of Occupational and Environmental Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, 13 Hangkong Road, Wuhan, 430030, Hubei, China.

Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, and State Key Laboratory of Environmental Health (Incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.

出版信息

Environ Sci Pollut Res Int. 2024 May;31(25):36910-36924. doi: 10.1007/s11356-024-33701-3. Epub 2024 May 17.

DOI:10.1007/s11356-024-33701-3
PMID:38758446
Abstract

Silicosis is an occupational lung disease because of exposure to silica dust in the workplace. Evidence on the spatiotemporal change of silicosis burden worldwide remains limited. This study utilized data extracted from the Global Burden of Disease Study 2019 to examine the numbers and age-standardized rates of incidence (ASIR), mortality (ASMR), and disability-adjusted life years (DALYs) caused by silicosis between 1990 and 2019. Average annual percentage changes (AAPCs) were calculated to evaluate the temporal trends of age-standardized indicators by sex, region, and socio-demographic index (SDI) since 1990. Results indicated an increase in new silicosis cases globally, rising by 64.61% from 84,426 in 1990 to 138,971 in 2019, with a sustained high number of DALYs attributed to this disease. Although the global age-standardized rates of incidence, mortality, and DALYs of silicosis have decreased since 1990, the number of new cases has increased in 168 countries and territories, and the ASIR of silicosis has also risen in 118 countries and territories, primarily in developing countries. Since 1990, the burden of silicosis among the elderly has significantly increased. Countries with higher SDI experienced a more rapid decline in the silicosis burden. Silicosis remains a public health problem that requires significant attention. Programs for prevention and elimination of this public health issue need to be established in more countries and territories. Protecting young workers from silica dust exposure is crucial to prevent the onset of silicosis in their later years and to reduce the disease burden among older workers.

摘要

矽肺是一种职业性肺部疾病,由工作场所暴露于二氧化硅粉尘引起。全球矽肺负担的时空变化证据仍然有限。本研究利用 2019 年全球疾病负担研究提取的数据,研究了 1990 年至 2019 年期间矽肺导致的发病人数和年龄标准化发病率(ASIR)、死亡率(ASMR)和伤残调整生命年(DALY)及其变化。通过计算平均年变化百分比(AAPC),评估了 1990 年以来按性别、地区和社会人口指数(SDI)划分的年龄标准化指标的时间趋势。结果表明,全球新发矽肺病例数呈上升趋势,1990 年为 84426 例,2019 年增至 138971 例,上升了 64.61%,且归因于该病的伤残调整生命年(DALY)数量持续较高。尽管自 1990 年以来,全球矽肺的发病率、死亡率和伤残调整生命年(DALY)的年龄标准化率有所下降,但168 个国家和地区的新发病例数有所增加,118 个国家和地区的矽肺发病率也有所上升,主要是在发展中国家。自 1990 年以来,老年人矽肺负担显著增加。SDI 较高的国家矽肺负担下降速度较快。矽肺仍然是一个公共卫生问题,需要引起高度关注。需要在更多的国家和地区制定预防和消除这一公共卫生问题的计划。保护年轻工人免受二氧化硅粉尘的侵害,对于防止他们晚年发病和降低老年工人的疾病负担至关重要。

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