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双气囊小肠镜与单气囊小肠镜:一项对照研究。

Double balloon enteroscopy versus single balloon enteroscopy: A comparative study.

机构信息

Department of Gastroenterology and Hepatology, Singapore General Hospital, Singapore, Singapore.

DUKE-NUS Graduate Medical School, Singapore, Singapore.

出版信息

Medicine (Baltimore). 2024 May 17;103(20):e38119. doi: 10.1097/MD.0000000000038119.

Abstract

Device assisted enteroscopy (DAE) like the double balloon enteroscopy (DBE) and single balloon enteroscopy (SBE) are postulated to ease small bowel examination and performance of therapy. However, studies comparing the effectiveness of these 2 modalities have yielded varying results. The aim of this study is to compare the efficacy and safety of SBE and DBE. We retrospectively reviewed records of patients who underwent DBE (n = 82) or SBE (n = 45) for small bowel exam in our unit from January 2014 to January 2022. Our primary outcomes were to compare the technical success and diagnostic success rates between DBE and SBE. Our secondary outcomes were to compare the therapeutic success, and complication rates. The main indications were suspected GI bleeding (DBE 41.5% vs SBE 48.9%), iron deficiency anemia (DBE 9.8% vs SBE 4.4%) and small bowel lesions (DBE 28.0% vs SBE 44.4%) detected either from prior capsule endoscopy or radiological imaging. Majority of the enteroscopy exam was by antegrade approach (DBE 67.1% vs SBE 77.8%). We found no significant difference in the technical success (DBE 95.1% vs SBE 97.8%, P = .46), diagnostic success (DBE 69.5% vs SBE 77.8%, P = .36) and the therapeutic success rate (DBE 63.2% vs SBE 54.3%, P = .09) between the groups. Complications occurred in 1 case from each group (mucosal tear). None of the complications were major. In patients who underwent enteroscopy, the diagnostic and therapeutic performance of SBE is similar to DBE. Both procedures were safe with low complication rates.

摘要

设备辅助小肠镜检查(DAE),如双气囊小肠镜(DBE)和单气囊小肠镜(SBE),被认为可以简化小肠检查和治疗操作。然而,比较这两种方式有效性的研究结果各不相同。本研究旨在比较 SBE 和 DBE 的疗效和安全性。我们回顾性分析了 2014 年 1 月至 2022 年 1 月期间在我院接受 DBE(n=82)或 SBE(n=45)检查的患者的记录。我们的主要研究终点是比较 DBE 和 SBE 的技术成功率和诊断成功率。次要研究终点是比较治疗成功率和并发症发生率。主要适应证为疑似胃肠道出血(DBE 占 41.5%,SBE 占 48.9%)、缺铁性贫血(DBE 占 9.8%,SBE 占 4.4%)和胶囊内镜或影像学检查发现的小肠病变(DBE 占 28.0%,SBE 占 44.4%)。大多数小肠镜检查采用顺行法(DBE 占 67.1%,SBE 占 77.8%)。我们发现两组在技术成功率(DBE 95.1%,SBE 97.8%,P=0.46)、诊断成功率(DBE 69.5%,SBE 77.8%,P=0.36)和治疗成功率(DBE 63.2%,SBE 54.3%,P=0.09)方面无显著差异。两组各有 1 例发生并发症(黏膜撕裂)。无严重并发症发生。在接受小肠镜检查的患者中,SBE 的诊断和治疗性能与 DBE 相似。两种方法均安全,并发症发生率低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b818/11098199/d29100bad34d/medi-103-e38119-g001.jpg

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