Key Laboratory of Occupational Environment and Health, Guangzhou Twelfth People's Hospital, Guangzhou, China.
Department of Health care, BaiYun Women and Children's Hospital and Health Institute, Guangzhou, China.
BMJ Open. 2024 May 17;14(5):e079955. doi: 10.1136/bmjopen-2023-079955.
This study aims to predict the risk of noise-induced hearing loss (NIHL) through a back-propagation neural network (BPNN) model. It provides an early, simple and accurate prediction method for NIHL.
Population based, a cross sectional study.
Han, China.
This study selected 3266 Han male workers from three automobile manufacturing industries.
Information including personal life habits, occupational health test information and occupational exposure history were collected and predictive factors of NIHL were screened from these workers. BPNN and logistic regression models were constructed using these predictors.
The input variables of BPNN model were 20, 16 and 21 important factors screened by univariate, stepwise and lasso-logistic regression. When the BPNN model was applied to the test set, it was found to have a sensitivity (TPR) of 83.33%, a specificity (TNR) of 85.92%, an accuracy (ACC) of 85.51%, a positive predictive value (PPV) of 52.85%, a negative predictive value of 96.46% and area under the receiver operating curve (AUC) is: 0.926 (95% CI: 0.891 to 0.961), which demonstrated the better overall properties than univariate-logistic regression modelling (AUC: 0.715) (95% CI: 0.652 to 0.777). The BPNN model has better predictive performance against NIHL than the stepwise-logistic and lasso-logistic regression model in terms of TPR, TNR, ACC, PPV and NPV (p<0.05); the area under the receiver operating characteristics curve of NIHL is also higher than that of the stepwise and lasso-logistic regression model (p<0.05). It was a relatively important factor in NIHL to find cumulative noise exposure, auditory system symptoms, age, listening to music or watching video with headphones, exposure to high temperature and noise exposure time in the trained BPNN model.
The BPNN model was a valuable tool in dealing with the occupational risk prediction problem of NIHL. It can be used to predict the risk of an individual NIHL.
本研究旨在通过反向传播神经网络(BPNN)模型预测噪声性听力损失(NIHL)的风险。它为 NIHL 提供了一种早期、简单、准确的预测方法。
基于人群的横断面研究。
中国汉族人群。
本研究从三家汽车制造企业中选择了 3266 名汉族男性工人。
收集个人生活习惯、职业健康检查信息和职业暴露史等信息,从这些工人中筛选出 NIHL 的预测因素。使用这些预测因素构建 BPNN 和逻辑回归模型。
BPNN 模型的输入变量为单因素、逐步和套索逻辑回归筛选出的 20、16 和 21 个重要因素。当将 BPNN 模型应用于测试集时,发现其敏感性(TPR)为 83.33%,特异性(TNR)为 85.92%,准确性(ACC)为 85.51%,阳性预测值(PPV)为 52.85%,阴性预测值为 96.46%,受试者工作特征曲线下面积(AUC)为 0.926(95%置信区间:0.891 至 0.961),优于单因素逻辑回归模型(AUC:0.715)(95%置信区间:0.652 至 0.777)。与逐步逻辑回归和套索逻辑回归模型相比,BPNN 模型在 TPR、TNR、ACC、PPV 和 NPV 方面对 NIHL 具有更好的预测性能(p<0.05);NIHL 的受试者工作特征曲线下面积也高于逐步和套索逻辑回归模型(p<0.05)。在训练好的 BPNN 模型中,累积噪声暴露、听觉系统症状、年龄、戴耳机听音乐或观看视频、高温暴露和噪声暴露时间是 NIHL 中相对重要的因素。
BPNN 模型是处理 NIHL 职业风险预测问题的一种有价值的工具。它可用于预测个体发生 NIHL 的风险。