细胞中的选择性浓缩规则。
Rules of selective condensation in cells.
作者信息
Phillips Michael, Ghosh Kingshuk
机构信息
Department of Physics and Astronomy, University of Denver, Denver, CO, USA.
出版信息
Nat Chem. 2024 Jul;16(7):1042-1044. doi: 10.1038/s41557-024-01525-w.
Abstract
Liquid droplets form in cells to concentrate specific biomolecules (while excluding others) in order to perform specific functions. The molecular mechanisms that determine whether different macromolecules undergo co-partitioning or exclusion has so far remained elusive. Now, two studies uncover key principles underlying this selectivity.
摘要
液滴在细胞中形成，以浓缩特定生物分子（同时排除其他分子）从而执行特定功能。到目前为止，决定不同大分子是共同分配还是相互排斥的分子机制仍不清楚。现在，两项研究揭示了这种选择性背后的关键原理。
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