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城市人群对纳洛酮及阿片类物质使用障碍药物的认知:一项横断面调查研究

Layperson knowledge on naloxone and medications for opioid use disorder in an urban population: a cross sectional survey study.

作者信息

Ramdin Christine, Zembrzuska Malgorzata, Zembrzuski Krzysztof, Nelson Lewis

机构信息

Department of Emergency Medicine, Rutgers New Jersey Medical School, Newark, NJ, USA.

School of Medicine, Rowan-Virtua School of Osteopathic Medicine, Stratford, NJ, USA.

出版信息

J Addict Dis. 2025 Apr-Jun;43(2):153-161. doi: 10.1080/10550887.2024.2353431. Epub 2024 May 19.

Abstract

BACKGROUND AND OBJECTIVES

There has been little research in an urban population regarding knowledge of harm reduction measures and treatment options. The objective of our study was to evaluate knowledge and perceptions of harm reduction measures and types of treatment available for opioid use disorder among patients and family in an urban emergency department (ED) waiting room.

METHODS

We conducted a single center, cross-sectional survey study that occurred between September 2021 and August 2022. A convenience sample of patients and family members that were above 18 and English speaking were recruited by research assistants. Participants were assessed on knowledge and preferences around drug treatment options and harm reduction. Data were summarized using descriptive statistics and compared using the Freeman-Halton/Kruskall-Wallis/Mann-Whitney tests. -Values were reported at the 0.05 significance level.

RESULTS

We collected 200 responses. Of these, 104 people had a connection to someone with a substance use disorder (SUD) and 50 had an SUD. Of those who had a connection to someone with SUD, 63 had heard of naloxone (60.6%, CI: [50.5, 69.9]). Fewer than 60% of respondents in each group had heard of Medications for Opioid Use Disorder (MOUD) ( = 0.46) and fewer than 50% thought that among people who use drugs that they knew would be interested in receiving treatment ( = 0.10).

DISCUSSION AND CONCLUSIONS

Our study found that among people who came to an urban emergency department, there was a lack of awareness of harm reduction and MOUD. Interventions should be put into place to educate on the importance of MOUD and harm reduction.

摘要

背景与目的

在城市人群中,关于减少伤害措施和治疗选择的知识研究较少。我们研究的目的是评估城市急诊科(ED)候诊室中患者及其家属对减少伤害措施以及阿片类物质使用障碍可用治疗类型的知识和看法。

方法

我们于2021年9月至2022年8月进行了一项单中心横断面调查研究。研究助理招募了年龄在18岁以上且讲英语的患者及其家属作为便利样本。参与者接受了关于药物治疗选择和减少伤害方面的知识及偏好评估。数据采用描述性统计进行汇总,并使用弗里曼 - 哈尔顿/克鲁斯卡尔 - 沃利斯/曼 - 惠特尼检验进行比较。P值在0.05显著性水平下报告。

结果

我们收集了200份回复。其中,104人与患有物质使用障碍(SUD)的人有关联,50人患有SUD。在与患有SUD的人有关联的人中,63人听说过纳洛酮(60.6%,置信区间:[50.5, 69.9])。每组中不到60%的受访者听说过阿片类物质使用障碍药物治疗(MOUD)(P = 0.46),不到50%的人认为在吸毒人群中他们知道会有兴趣接受治疗(P = 0.10)。

讨论与结论

我们的研究发现,在前往城市急诊科的人群中,对减少伤害和MOUD缺乏认识。应采取干预措施,就MOUD和减少伤害的重要性进行教育。

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