疑似秋水仙碱诱发的晚期心肌破裂，发生于急性下壁ST段抬高型心肌梗死延迟就诊之后。
Suspected colchicine-induced late myocardial rupture occurring after the late presentation of acute inferior ST-elevation myocardial infarction.
作者信息
Niyas Abdullah Mohamed, Haseefa Fathima, Cox Jordy Charles, Movahed Mohammad Reza
机构信息
University of Arizona College of Medicine Phoenix, AZ, USA.
Creighton University Phoenix, AZ, USA.
出版信息
Am J Cardiovasc Dis. 2024 Apr 15;14(2):116-120. doi: 10.62347/FXLN8938. eCollection 2024.
Abstract
Colchicine is one of the established drugs of choice for post-myocardial infarction (MI) induced pericarditis, given its anti-inflammatory properties. Recently, colchicine received FDA approval for secondary prevention of atherosclerotic cardiovascular disease, which leads to concerns regarding its anti-healing effects on myocardial tissue post-infarction. We present a case of a suspected colchicine-induced myocardial rupture in an elderly male, who presented with a syncopal episode while on colchicine three weeks after the late presentation of infero-posterior ST-elevation myocardial infarction.
摘要
秋水仙碱因其抗炎特性，是心肌梗死（MI）后诱发心包炎的既定首选药物之一。最近，秋水仙碱获得了美国食品药品监督管理局（FDA）对动脉粥样硬化性心血管疾病二级预防的批准，这引发了人们对其对心肌梗死后心肌组织抗愈合作用的担忧。我们报告一例老年男性疑似秋水仙碱诱发心肌破裂的病例，该患者在出现下后壁ST段抬高型心肌梗死后三周，服用秋水仙碱期间出现晕厥发作。
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