Alanazi Shahad N, Bali Dana A, Alwagdani Nawaf M, Mal Youssof, Alkhatieb Maram T, AlJaaly Hattan A, Fadel Zahir T
Division of Plastic Surgery, Department of Surgery, Faculty of Medicine, King Abdulaziz University Jeddah, Saudi Arabia.
Department of Orthopedic Surgery, King Faisal Specialist Hospital and Research Centre Riyadh, Saudi Arabia.
Int J Burns Trauma. 2024 Apr 15;14(2):32-37. doi: 10.62347/GHPO4831. eCollection 2024.
This case report describes a unique scenario in which antimycobacterial-induced peripheral neuropathy (PN) culminates in severe bilateral foot frostbite. Drug-induced peripheral neuropathy (DIPN) is explored in the context of TB treatment, highlighting the role of medications such as isoniazid (INH) and their potential to cause PN. The report highlights the importance of identifying PN in patients undergoing antimycobacterial treatment. Early recognition and proper management of PN is crucial to prevent complications. Notably, the report advocates for patient education regarding medication side effects and avoiding harmful practices, such as ice immersion, to alliviate neuropathic pain. Emphasis is directed towards the need for a multidisciplinary approach to patient care and a focus on preventative strategies to improve patient outcomes and avoid severe debilitating complications.
本病例报告描述了一种独特的情况,即抗分枝杆菌药物引起的周围神经病变(PN)最终导致严重的双侧足部冻伤。在结核病治疗的背景下探讨了药物性周围神经病变(DIPN),强调了异烟肼(INH)等药物的作用及其导致PN的可能性。该报告强调了在接受抗分枝杆菌治疗的患者中识别PN的重要性。早期识别和妥善管理PN对于预防并发症至关重要。值得注意的是,该报告提倡对患者进行关于药物副作用的教育,并避免有害行为,如冰敷,以减轻神经性疼痛。重点是需要采取多学科方法进行患者护理,并注重预防策略,以改善患者预后并避免严重的致残性并发症。