Akıncı Erhan, İnce Bahri
Department of Psychiatry, Canakkale Onsekiz Mart University School of Medicine, Canakkale, Turkey.
Department of Psychiatry, Bakirkoy Training and Research Hospital for Psychiatry, Neurology and Neurosurgery, İstanbul, Turkey.
Psychiatry Clin Psychopharmacol. 2021 Jun 1;31(2):213-218. doi: 10.5152/pcp.2021.21335. eCollection 2021 Jun.
This study aimed to evaluate and follow-up the process of acute treatment for depression in terms of activity and sleep efficiency using actigraphy, and thus increase the opportunities for objective measurement in the monitoring of treatment.
A total of 20 patients with depression, and 22 and age- and gender-matched healthy volunteers were included in the study. All subjects were evaluated using a sociodemographic data form, the Hamilton Depression Rating Scale (HDRS), and actigraphy for measurement of motor activity and sleep efficiency.
The activity levels and sleep efficiency of the controls were significantly higher than the pre-and post-treatment activity levels and sleep efficiency of the patients. After the treatment process, both motor activity and sleep efficiency were found to be significantly increased in the patients. A highly significant negative correlation was found between the HDRS scores and average activity counts for active intervals ( = -0.779, < .001), and between the HDRS scores and sleep efficiency ( = -0.616, < .001). On the other hand, a significant negative effect was found between depression and average activity counts for active intervals (RR:0.880; 95% CI:0.782-0.991).
Actigraphy is a useful technique for quantifying physical activities and sleep efficiency in depressed patients. Furthermore, it may provide objective follow-up data in assessing the effects of treatment for depression.
本研究旨在通过活动记录仪评估和随访抑郁症急性治疗过程中的活动和睡眠效率，从而增加治疗监测中客观测量的机会。
本研究纳入了20例抑郁症患者以及22名年龄和性别匹配的健康志愿者。所有受试者均使用社会人口统计学数据表格、汉密尔顿抑郁量表（HDRS）以及用于测量运动活动和睡眠效率的活动记录仪进行评估。
对照组的活动水平和睡眠效率显著高于患者治疗前和治疗后的活动水平及睡眠效率。治疗过程结束后，患者的运动活动和睡眠效率均显著提高。HDRS评分与活动时间段的平均活动计数之间存在高度显著的负相关（r = -0.779，P <.001），HDRS评分与睡眠效率之间也存在高度显著的负相关（r = -0.616，P <.001）。另一方面，抑郁症与活动时间段的平均活动计数之间存在显著的负效应（RR：0.880；95%CI：0.782 - 0.991）。
活动记录仪是一种用于量化抑郁症患者身体活动和睡眠效率的有用技术。此外，它可能为评估抑郁症治疗效果提供客观的随访数据。
