Paulsingh Christian N, Riaz Muhammad Faisal, Garg Gourav, Umeano Lotanna, Iftikhar Sadaf, Alhaddad Sarah F, Hamid Pousette
Pathology, St. George's University School of Medicine, St. George's, GRD.
Internal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Cureus. 2024 Apr 18;16(4):e58553. doi: 10.7759/cureus.58553. eCollection 2024 Apr.
The systematic review investigates the impact of different nutrients and dietary patterns on metabolism and immunity to answer the research question: "Can personalized nutritional approaches boost immunity?" The importance of diet in supporting the immune system has come to light in today's environment, where a strong immune system is crucial for protection against infectious illnesses, as highlighted by the COVID-19 pandemic. This systematic review adhered to the guidelines outlined in the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020. Four databases were screened for relevant data published in 2022-2023: PubMed, PubMed Central (PMC), MEDLINE, and Cochrane Library. Inclusion and exclusion criteria were utilized, and 13 papers were finalized after screening and employing the quality appraisal tool Cochrane Bias assessment for randomized controlled trials (RCT). Personalized nutrition can strengthen immunity and enhance overall health by adjusting dietary recommendations and following a person's genetic makeup, lifestyle, and health state. An adequate supply of vitamins, minerals, proteins, and fatty acids as well as an optimum caloric intake are essential for immune health, and individual requirements can vary significantly due to genetic factors, lifestyle choices, and underlying health conditions. Personalized nutrition considers these factors, enabling tailored dietary recommendations to address specific nutrient needs and optimize nutrient intake, leading to better health outcomes. The review concludes that personalized nutrition is more effective than a one-size-fits-all approach in boosting immunity, and its potential impact on health and immune function is highly important.
这项系统评价研究了不同营养素和饮食模式对新陈代谢和免疫力的影响，以回答研究问题：“个性化营养方法能否增强免疫力？”在当今环境中，饮食对支持免疫系统的重要性已显现出来，正如新冠疫情所凸显的那样，强大的免疫系统对于预防传染病至关重要。本系统评价遵循了《系统评价和Meta分析优先报告项目》（PRISMA）2020中概述的指南。对四个数据库进行了筛选，以获取2022年至2023年发表的相关数据：PubMed、PubMed Central（PMC）、MEDLINE和Cochrane图书馆。采用了纳入和排除标准，在筛选并使用随机对照试验（RCT）的质量评估工具Cochrane偏倚评估后，最终确定了13篇论文。个性化营养可以通过调整饮食建议并根据个人的基因构成、生活方式和健康状况来增强免疫力并改善整体健康。充足的维生素、矿物质、蛋白质和脂肪酸供应以及最佳热量摄入对免疫健康至关重要，由于遗传因素、生活方式选择和潜在健康状况的不同，个体需求可能有很大差异。个性化营养考虑了这些因素，能够制定量身定制的饮食建议，以满足特定的营养需求并优化营养摄入，从而带来更好的健康结果。该评价得出结论，个性化营养在增强免疫力方面比一刀切的方法更有效，其对健康和免疫功能的潜在影响非常重要。
