Caudill J W, Streeten B W, Tso M O
Ophthalmology. 1985 Aug;92(8):1153-8. doi: 10.1016/s0161-6420(85)33914-3.
Three cases of persistent hyperplastic primary vitreous (PHPV) showing a ruptured lens capsule and a phacoanaphylactoid reaction are presented. In two cases, there was evidence that the lens had been clinically clear in the presence of a ruptured capsule and posterior cortical granulomatous reaction. The capsular rupture and granulomatous reaction can begin in utero, as shown by the third case, a premature who died at one day of age. It is suggested that a phacoanaphylactoid reaction can contribute to the lens swelling, cataract, and anterior chamber narrowing which often initiate the downhill course in eyes with PHPV. The immunological implications of this reaction are discussed.
本文报告了3例持续性增生性原发性玻璃体（PHPV）病例，这些病例均显示晶状体囊破裂及类晶状体过敏性反应。在2例病例中，有证据表明，在晶状体囊破裂及后皮质肉芽肿反应存在的情况下，晶状体在临床上是透明的。如第3例病例所示，囊破裂及肉芽肿反应可在子宫内就开始，该例为一名出生1天即死亡的早产儿。提示类晶状体过敏性反应可促使晶状体肿胀、白内障形成及前房变窄，而这些情况常引发PHPV患眼病情恶化。本文还讨论了该反应的免疫学意义。
