Yazar Menekşe Sıla, Şenyaşar Meterelliyoz Kumru
Department of Psychiatry, Altınbas University School of Medicine, Istanbul, Turkey.
Department of Psychiatry, Bakirkoy Prof. Dr. Mazhar Osman Research and Training Hospital for Neurology, Neurosurgery and Psychiatry, Istanbul, Turkey.
Psychiatry Clin Psychopharmacol. 2021 Dec 1;31(4):434-441. doi: 10.5152/pcp.2021.21039. eCollection 2021 Dec.
The role of anxiety sensitivity in the occurrence of clinical anxiety symptoms that accompany medical diseases is increasingly well understood. This study aimed to investigate the role of anxiety sensitivity in the occurrence of clinical anxiety symptoms in multiple sclerosis patients.
This cross-sectional research was conducted on 105 multiple sclerosis patients aged between 18 and 65 years. Hospital Anxiety Depression Scale and The Anxiety Sensitivity Index-3 (ASI-3) were used to assess depression, anxiety, and anxiety sensitivity. Participants with significant levels of anxiety were compared to those who were not anxious.
Anxiety Sensitivity Index total and Anxiety Sensitivity Index cognitive, physical, and social concerns subdomains, Hospital Anxiety Depression Scale and Hospital Anxiety Depression total scores were significantly higher in the anxious group than the non-anxious group ( < .05). The correlation analysis revealed a positive and significant correlation between the scales that were used to assess anxiety, depression, and anxiety sensitivity ( < .05). Depression levels and Anxiety Sensitivity Index social concerns subdomain remained as the most significant variables in the prediction of anxiety levels (OR 1.37, 95% CI 1.17-1.61, < .001 and OR 1.22, 95% CI 1.08-1.38, =.0009, respectively).
Anxiety sensitivity is related to the occurrence of clinical anxiety symptoms in multiple sclerosis patients. Depression and Anxiety Sensitivity Index social concerns subdomain predict the occurrence of clinical anxiety symptoms.
焦虑敏感性在伴随医学疾病出现的临床焦虑症状中的作用日益为人所理解。本研究旨在调查焦虑敏感性在多发性硬化症患者临床焦虑症状发生中的作用。
本横断面研究针对105名年龄在18至65岁之间的多发性硬化症患者进行。使用医院焦虑抑郁量表和焦虑敏感性指数-3（ASI-3）来评估抑郁、焦虑和焦虑敏感性。将焦虑水平显著的参与者与无焦虑的参与者进行比较。
焦虑组的焦虑敏感性指数总分、焦虑敏感性指数认知、身体和社交担忧子领域、医院焦虑抑郁量表及医院焦虑抑郁总分均显著高于非焦虑组（<.05）。相关性分析显示，用于评估焦虑、抑郁和焦虑敏感性的量表之间存在显著正相关（<.05）。抑郁水平和焦虑敏感性指数社交担忧子领域在预测焦虑水平时仍是最显著的变量（分别为OR 1.37，95%CI 1.17 - 1.61，<.001和OR 1.22，95%CI 1.08 - 1.38，=.0009）。
焦虑敏感性与多发性硬化症患者临床焦虑症状的发生有关。抑郁和焦虑敏感性指数社交担忧子领域可预测临床焦虑症状的发生。
