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毛囊性银屑病的临床、皮肤镜及组织病理学研究

A Clinical, Dermoscopic, and Histopathological Study of Follicular Psoriasis.

作者信息

Saep Maqbool, Shenoy Manjunath Mala, Rao Anuradha C K, Pinto Malcolm, Hegde Spandana Prakash, Iqbal Amina Asfiya M

机构信息

Department of Dermatology, Venereology and Leprosy, Yenepoya Medical College, Yenepoya (Deemed to be University), Mangalore, Karnataka, India.

Department of Pathology, Yenepoya Medical College, Yenepoya (Deemed to be University), Mangalore, Karnataka, India.

出版信息

Int J Trichology. 2023 Jul-Aug;15(4):127-132. doi: 10.4103/ijt.ijt_168_20. Epub 2024 Apr 5.

DOI:10.4103/ijt.ijt_168_20
PMID:38765718
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11098143/
Abstract

INTRODUCTION

Follicular psoriasis is one of the underdiagnosed clinical types of psoriasis. Literature is grossly limited to anecdotal case reports and series. Clinical and investigational aspects are not studied in depth.

MATERIALS AND METHODS

A study was conducted to determine the frequency of follicular psoriasis, which includes cases with an exclusive or substantial number of follicular lesions. We analyzed the clinical, dermoscopic, and histopathological features of follicular psoriasis in a descriptive study.

RESULTS

A total of 117 patients with psoriasis were screened. An exclusive or substantial number of follicular lesions were found in 22 patients. Four patients had exclusively follicular lesions and others were psoriasis vulgaris with follicular psoriasis. Dermoscopy revealed perifollicular scaling and white homogeneous area with normal terminal hair in all cases. Vascular features were visible in 14 cases and all had dotted vessels, with four having additional globules. Twenty patients revealed one or more features suggestive of follicular psoriasis on histopathology.

CONCLUSION

Follicular lesions can appear exclusively or can coexist with plaque type of lesions in psoriasis. They may indicate early psoriasis lesions. Dermoscopy is a useful and rapid tool to confirm the diagnosis of follicular psoriasis. Histopathology, though confirmatory, demands an astute interpretational skill. Diagnosis of follicular psoriasis can have therapeutic implications.

摘要

引言

毛囊性银屑病是银屑病临床类型中诊断不足的类型之一。文献资料极为有限,多为个案报道和系列病例报告。临床和研究方面尚未深入研究。

材料与方法

开展一项研究以确定毛囊性银屑病的发病率,该研究纳入了仅出现毛囊性损害或毛囊性损害占多数的病例。我们在一项描述性研究中分析了毛囊性银屑病的临床、皮肤镜和组织病理学特征。

结果

共筛查了117例银屑病患者。22例患者出现仅有的或多数的毛囊性损害。4例患者仅有毛囊性损害,其他患者为寻常型银屑病合并毛囊性银屑病。皮肤镜检查显示所有病例均有毛囊周围鳞屑和白色均质区,终毛正常。14例可见血管特征,均有点状血管,4例有额外的小球状血管。20例患者组织病理学显示一项或多项提示毛囊性银屑病的特征。

结论

毛囊性损害可单独出现,也可与银屑病斑块型损害并存。它们可能提示早期银屑病损害。皮肤镜检查是确诊毛囊性银屑病的有用且快速的工具。组织病理学虽可确诊,但需要敏锐的解读技巧。毛囊性银屑病的诊断可能具有治疗意义。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc31/11098143/82ac30f2e55b/IJT-15-127-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc31/11098143/1d1a42ab9460/IJT-15-127-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc31/11098143/d6320e231ca2/IJT-15-127-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc31/11098143/997141375ffd/IJT-15-127-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc31/11098143/82ac30f2e55b/IJT-15-127-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc31/11098143/1d1a42ab9460/IJT-15-127-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc31/11098143/d6320e231ca2/IJT-15-127-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc31/11098143/997141375ffd/IJT-15-127-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc31/11098143/82ac30f2e55b/IJT-15-127-g004.jpg

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