Elsabaawy Maha, Elbahr Osama, Edrees Ahmed, Badr Reda, Kamal Ahmed, Afify Sameh
Department of Hepatology and Gastroenterology, National Liver Institute, Menoufia University, Shebeen El-Koum, Menoufia, Egypt.
Clin Exp Hepatol. 2024 Mar;10(1):14-19. doi: 10.5114/ceh.2024.136216. Epub 2024 Mar 17.
Managing patients with liver cirrhosis and gastric hyperplastic polyps (GHPs) is challenging. Despite being the standard technique for resection of GHPs, hot snare polypectomy (HSP) is risky in the setting of coagulation disorders associated with liver cirrhosis. The aim of the study was to assess the efficacy and safety of endoscopic band ligation (EBL), compared to HSP in resecting GHPs in cirrhotic patients. One hundred consecutive adults with liver cirrhosis and sessile or pedunculated GHPs were enrolled from December 2018 to December 2020. Cases were non-blindly randomized (1 : 1) to two groups to have GHPs managed by either EBL (group I) or HSP (group II). Data of demographic, clinical, and pathological factors, hospitalization expenses and outcomes of both treatment maneuvers were collected and statistically analyzed. Upper endoscopy was repeated for all patients at 3, 6 and 12 months after treatment for recurrence detection. Between the two procedures, the mean operational time was significantly shorter in the EBL than the HSP group (15.1 ±3.80 min vs. 36.6 ±6.72 min, < 0.001). Concerning complications, 94% of EBL cases had reported no complications compared to 78% with HSP. Bleeding occurred only with HSP (20%) with urgent need for adrenaline and/or argon plasma coagulation ( = 0.003). Regarding cost, it was significantly lower in EBL than HSP (280 ±2.02 EGP vs. 390 ±181.8 EGP, < 0.001). However, the recurrence rate of GHPs and number of needed sessions were not significantly different. EBL proved to be a safer, more rapid, and economic maneuver when compared to HSP on resecting GHPs in patients with liver cirrhosis.
管理肝硬化合并胃增生性息肉(GHP)的患者具有挑战性。尽管热圈套息肉切除术(HSP)是切除GHP的标准技术,但在与肝硬化相关的凝血障碍情况下,该手术存在风险。本研究的目的是评估内镜下套扎术(EBL)与HSP相比,在切除肝硬化患者GHP方面的疗效和安全性。2018年12月至2020年12月,连续纳入了100例患有肝硬化且有广基或有蒂GHP的成年人。病例被非盲随机(1:1)分为两组,分别采用EBL(第一组)或HSP(第二组)治疗GHP。收集了两组患者的人口统计学、临床和病理因素、住院费用以及两种治疗方法的结果,并进行了统计分析。所有患者在治疗后3、6和12个月重复进行上消化道内镜检查以检测复发情况。在这两种手术中,EBL组的平均手术时间明显短于HSP组(15.1±3.80分钟对36.6±6.72分钟,P<0.001)。关于并发症,94%的EBL病例报告无并发症,而HSP组为78%。仅HSP组发生了出血(20%),急需肾上腺素和/或氩气刀凝血(P = 0.003)。在费用方面,EBL组明显低于HSP组(280±2.02埃及镑对390±181.8埃及镑,P<0.001)。然而,GHP的复发率和所需治疗次数没有显著差异。与HSP相比,EBL在切除肝硬化患者的GHP时被证明是一种更安全、更快速且更经济的手术方法。