School of Health Science, International Medical University, Kuala Lumpur 57000, Malaysia.
Division of Biomedical Science and Biotechnology, School of Health Science, International Medical University, Kuala Lumpur 57000, Malaysia.
Fitoterapia. 2024 Jul;176:106025. doi: 10.1016/j.fitote.2024.106025. Epub 2024 May 18.
Algae and its metabolites have been a popular subject of research in numerous fields over the years. Various reviews have been written on algal bioactive components, but a specific focus on Antarctic-derived algae is seldom reviewed. Due to the extreme climate conditions of Antarctica, it is hypothesized that the acclimatized algae may have given rise to a new set of bioactive compounds as a result of adaptation. Although most studies done on Antarctic algae are based on ecological and physiological studies, as well as in the field of nanomaterial synthesis, some studies point out the potential therapeutic properties of these compounds. As an effort to shed light on a different application of Antarctic algae, this review focuses on evaluating its different medicinal properties, including antimicrobial, anticancer, antioxidative, anti-inflammatory, and skin protective effects.
多年来，藻类及其代谢产物一直是众多领域研究的热门课题。已经有许多关于藻类生物活性成分的综述，但很少有专门针对南极来源藻类的综述。由于南极洲的极端气候条件，人们推测适应这些环境的藻类可能由于适应而产生了一组新的生物活性化合物。尽管大多数对南极藻类的研究都是基于生态学和生理学研究，以及纳米材料合成领域，但一些研究指出了这些化合物的潜在治疗特性。为了阐明南极藻类的另一种应用，本综述重点评估了其不同的药用特性，包括抗菌、抗癌、抗氧化、抗炎和皮肤保护作用。
