Chen Shuyi, Chen Sumin, Yu Xin, Wan Caijing, Wang Ying, Peng Lianxin, Li Qiang
Key Laboratory of Coarse Cereal Processing, Ministry of Agriculture and Rural Affairs, Sichuan Engineering & Technology Research Center of Coarse Cereal Industrialization, School of Food and Biological Engineering, Chengdu University, Chengdu 610106, China.
Foods. 2025 Jan 10;14(2):207. doi: 10.3390/foods14020207.
Lipopeptides (LPs) are widely sourced surface-active natural products with a wide range of functions and low toxicity, high potency, and good biodegradability. In this paper, we summarize, for the first time, the plant, animal, microbial, and synthetic sources of LPs. We also introduce the applications of LPs in food and human health, including (1) LPs can inhibit the growth of food microorganisms during production and preservation. They can also be added to food packaging materials for preservation and freshness during transportation, and can be used as additives to improve the taste of food. (2) LPs can provide amino acids and promote protein synthesis and cellular repair. Due to their broad-spectrum antimicrobial properties, they exhibit good anticancer effects and biological activities. This review summarizes, for the first time, the sources of LPs and their applications in food and human health, laying the foundation for the development and application of LPs.
脂肽（LPs）是来源广泛的表面活性天然产物，具有多种功能，且毒性低、活性高、生物降解性好。本文首次总结了脂肽的植物、动物、微生物及合成来源。我们还介绍了脂肽在食品和人类健康方面的应用，包括：（1）脂肽在食品生产和保存过程中可抑制食品微生物生长。它们还可添加到食品包装材料中，在运输过程中起到保鲜作用，并且可用作添加剂来改善食品口感。（2）脂肽可提供氨基酸，促进蛋白质合成和细胞修复。由于其具有广谱抗菌特性，因而展现出良好的抗癌效果和生物活性。本综述首次总结了脂肽的来源及其在食品和人类健康方面的应用，为脂肽的开发和应用奠定了基础。
