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睡眠与先天免疫之间的关系。

The relationship between sleep and innate immunity.

作者信息

Lee Yoonkyung, Park Kyung-Il

机构信息

Department of Neurology, Dong-A University Hospital, Busan, Korea.

Department of Neurology, Seoul National University Hospital, Seoul, Korea.

出版信息

Encephalitis. 2024 Oct;4(4):69-75. doi: 10.47936/encephalitis.2024.00017. Epub 2024 May 21.

DOI:10.47936/encephalitis.2024.00017
PMID:38769055
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11472141/
Abstract

Sleep regulates inflammatory responses, and the innate immune system affects sleep. Interleukin-1 beta, tumor necrosis factor alpha, growth hormone-releasing hormone, prolactin, and nitric oxide are somnogenic substances. Sleep deprivation, such as chronic insomnia or obstructive sleep apnea, affects cytokine production, glial function, natural killer cell activity, and inflammasome function. This review will discuss the relationship between sleep and innate immunity.

摘要

睡眠调节炎症反应，而先天免疫系统影响睡眠。白细胞介素-1β、肿瘤坏死因子α、生长激素释放激素、催乳素和一氧化氮是促眠物质。睡眠剥夺，如慢性失眠或阻塞性睡眠呼吸暂停，会影响细胞因子产生、神经胶质细胞功能、自然杀伤细胞活性和炎性小体功能。本综述将讨论睡眠与先天免疫之间的关系。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/44ab/11472141/76cb71d2108f/encephalitis-2024-00017f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/44ab/11472141/76cb71d2108f/encephalitis-2024-00017f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/44ab/11472141/76cb71d2108f/encephalitis-2024-00017f1.jpg

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本文引用的文献

1
Sleep regulates innate immunity.睡眠调节先天免疫。
Nat Immunol. 2024 Jan;25(1):3. doi: 10.1038/s41590-023-01727-3.
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Prolonged sleep deprivation induces a cytokine-storm-like syndrome in mammals.长期睡眠剥夺会在哺乳动物中诱导出一种细胞因子风暴样综合征。
Cell. 2023 Dec 7;186(25):5500-5516.e21. doi: 10.1016/j.cell.2023.10.025. Epub 2023 Nov 27.
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Heat of the night: sleep disturbance activates inflammatory mechanisms and induces pain in rheumatoid arthritis.炎夏之夜：睡眠障碍激活炎症机制并引发类风湿性关节炎疼痛。
Nat Rev Rheumatol. 2023 Sep;19(9):545-559. doi: 10.1038/s41584-023-00997-3. Epub 2023 Jul 24.
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Narcolepsy, autoimmunity, and influenza A H1N1 vaccination.发作性睡病、自身免疫与甲型H1N1流感疫苗接种
Encephalitis. 2021 Apr;1(2):31-35. doi: 10.47936/encephalitis.2021.00010. Epub 2021 Mar 23.
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Sleep disturbances in autoimmune encephalitis.自身免疫性脑炎中的睡眠障碍
Encephalitis. 2023 Jan;3(1):1-6. doi: 10.47936/encephalitis.2022.00073. Epub 2022 Dec 26.
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Sleep deprivation and NLRP3 inflammasome: Is there a causal relationship?睡眠剥夺与NLRP3炎性小体：是否存在因果关系？
Front Neurosci. 2022 Dec 22;16:1018628. doi: 10.3389/fnins.2022.1018628. eCollection 2022.
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Circadian Disruption and Consequences on Innate Immunity and Inflammatory Response.昼夜节律紊乱及其对先天免疫和炎症反应的影响。
Int J Mol Sci. 2022 Nov 8;23(22):13722. doi: 10.3390/ijms232213722.
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Microglia are involved in the protection of memories formed during sleep deprivation.小胶质细胞参与对睡眠剥夺期间形成的记忆的保护。
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Sleep Deprivation Disturbs Immune Surveillance and Promotes the Progression of Hepatocellular Carcinoma.睡眠剥夺扰乱免疫监视并促进肝细胞癌的进展。
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Innate Immunity Promotes Sleep through Epidermal Antimicrobial Peptides.先天免疫通过表皮抗菌肽促进睡眠。
Curr Biol. 2021 Feb 8;31(3):564-577.e12. doi: 10.1016/j.cub.2020.10.076. Epub 2020 Nov 30.