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通过将引流套管尖端推进上腔静脉可提高静脉-静脉体外膜肺氧合期间的动脉血氧分压:一例报告

Arterial oxygen pressure during veno-venous extracorporeal membrane oxygenation may be increased by advancing the tip of the drainage cannula into the superior vena cava: a case report.

作者信息

Nakamura Tomoyuki, Kuriyama Naohide, Hara Yoshitaka, Komura Hidefumi, Hoshino Naoki, Miyamoto Soshi, Sawada Ken, Kawaji Takahiro, Komatsu Satoshi, Nishida Osamu

机构信息

Department of Anesthesiology and Critical Care Medicine, Fujita Health University School of Medicine, 1-98 Dengakugakubo, Kutsukake-cho, Toyoake, Aichi, 470-1192, Japan.

Department of Cardiology, Fujita Health University School of Medicine, Toyoake, Japan.

出版信息

J Artif Organs. 2025 Mar;28(1):95-101. doi: 10.1007/s10047-024-01448-w. Epub 2024 May 21.

Abstract

A simple and robust method for veno-venous extracorporeal membrane oxygenation (V-V ECMO) involves a drainage cannula into the inferior vena cava via the femoral vein (FV) and a reinfusion cannula into the right atrium (RA) via the internal jugular vein (IJV) (F-J configuration). However, with this method, the arterial oxygen (PaO) is said to remain below 100 mmHg.Since recently, in our ICU, to prevent drainage failure, we apply a modification from the commonly practiced F-J configuration by advancing the tip of the drainage cannula inserted via the FV into the superior vena cava (SVC) and crossing the reinfusion cannula inserted via the IJV in the RA (F(SVC)-J(RA) configuration). We experienced that this modification can be associated with unexpectedly high PaO values, which here we investigated in detail.Veno-arteriovenous ECMO was induced in a 65-year-old male patient who suffered from repeated cardiac arrest due to acute respiratory distress syndrome. His chest X-ray images showed white-out after lung rest setting, consistent with near-absence of self-lung ventilation. Cardiac function recovered and the system was converted to F(SVC)-J(RA) configuration, after which both PaO and partial pressure of pulmonary arterial oxygen values remained high above 200 mmHg. Transesophageal echocardiography could not detect right-to-left shunt, and more efficient drainage of the native venous return flow compared to common F-J configuration may explain the increased PaO.Although the F(SVC)-J(RA) configuration is a small modification of the F-J configuration, it seems to provide a revolutionary improvement in the ECMO field by combining robustness/simplicity with high PaO values.

摘要

一种简单且可靠的静脉-静脉体外膜肺氧合(V-V ECMO)方法,是通过股静脉(FV)将引流插管置入下腔静脉,并通过颈内静脉(IJV)将再灌注插管置入右心房(RA)(F-J配置)。然而,据说采用这种方法时,动脉血氧(PaO)会一直低于100mmHg。最近,在我们的重症监护病房(ICU),为防止引流失败,我们对常用的F-J配置进行了改进,即将经FV插入的引流插管尖端推进至上腔静脉(SVC),并使经IJV插入RA的再灌注插管交叉(F(SVC)-J(RA)配置)。我们发现这种改进可能会带来意想不到的高PaO值,在此我们进行了详细研究。

一名65岁男性患者因急性呼吸窘迫综合征反复心脏骤停,接受了静脉-动脉-静脉ECMO治疗。他的胸部X光片显示在肺休息状态下呈白色,这与自身肺通气几乎缺失一致。心脏功能恢复后,系统转换为F(SVC)-J(RA)配置,此后PaO和肺动脉血氧分压值均保持在200mmHg以上的高水平。经食管超声心动图未检测到右向左分流,与常见的F-J配置相比,对天然静脉回流的更有效引流可能解释了PaO的升高。

尽管F(SVC)-J(RA)配置是对F-J配置的微小改进,但它似乎通过将稳健性/简易性与高PaO值相结合,在ECMO领域带来了革命性的进步。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1eba/11832550/40b092140efd/10047_2024_1448_Fig1_HTML.jpg

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