Galea P, D'amato B, Goel K M
Scott Med J. 1985 Jul;30(3):164-7. doi: 10.1177/003693308503000308.
Fifty-six children with JCA have attended the Rheumatology Clinic at the Royal Hospital for Sick Children, Glasgow, over the past five years. Eleven have monoarthritis, 21 pauciarthritis and 24 polyarthritis. Seven children with pauciarthritis and one with monoarthritis developed ocular complications. Of these six were girls. In six children the arthritis preceded the uveitis. In one child arthritis and uveitis presented at the same time and in another the uveitis preceded the arthritis by one year. All were treated with steroids (7 topically, 1 systemically) and topical mydriatic agents. After an initial response the uveitis persisted as a low-grade inflammation gradually leading to secondary complications and increasing loss of vision. Only two patients enjoy normal vision at present. The importance of routine slit-lamp microscopy in all children with JCA is stressed, especially in those with pauciarthritis and antinuclear antibodies.
在过去五年中,56名患有青少年慢性关节炎(JCA)的儿童前往格拉斯哥皇家儿童医院的风湿病诊所就诊。其中11人患单关节炎,21人患少关节炎,24人患多关节炎。7名患少关节炎的儿童和1名单关节炎儿童出现了眼部并发症。这些患儿中有6名是女孩。在6名儿童中,关节炎先于葡萄膜炎出现。1名儿童的关节炎和葡萄膜炎同时出现,另1名儿童的葡萄膜炎比关节炎早出现一年。所有患儿均接受了类固醇治疗(7名局部用药,1名全身用药)以及局部散瞳剂治疗。在最初的反应之后,葡萄膜炎持续存在,呈低度炎症,逐渐导致继发性并发症并使视力不断丧失。目前只有两名患者视力正常。强调了对所有JCA患儿进行常规裂隙灯显微镜检查的重要性,尤其是对那些患少关节炎且有抗核抗体的患儿。