Shadvar Neda, Akrami Sousan, Mousavi Sagharchi Seyyed-Mohammad-Amin, Askandar Rafee Habib, Merati Alireza, Aghayari Masoomeh, Kaviani Nikki, Afkhami Hamed, Kashfi Mojtaba
Department of Microbiology and Parasitology, School of Medicine, Bushehr University of Medical Sciences, Bushehr, Iran.
Student Research Committee, Bushehr University of Medical Sciences, Bushehr, Iran.
Front Microbiol. 2024 May 7;15:1379209. doi: 10.3389/fmicb.2024.1379209. eCollection 2024.
Gastric ulcers and gastric cancer are brought on by the bacteria, which colonizes under the stomach mucous membrane. Different medication regimens are used to remove it, but the illness returns and becomes more resistant, which lowers the treatment rates. Additionally, this bacterium now exhibits a skyrocketing level of multi-drug resistance, necessitating recurrent therapeutic treatments. The negative effects of synthetic medications in comparison to conventional therapies are another significant factor in favor of non-pharmacological therapy. The most significant side effects of popular anti-gastric ulcer medications include nausea, vomiting, and diarrhea. Stomach ulcers have previously been treated with herbal remedies and complementary treatments like probiotics. When probiotics are ingested, the host experiences several advantages that may be brought about by altering the bacterial flora in the digestive system. Additionally, stronger-acting chemical compounds and plant extracts can be employed to treat patients. In this article, we look at the substances and medications that are utilized in place of synthetic stomach ulcer-curing treatments.
胃溃疡和胃癌是由这种在胃黏膜下定植的细菌引起的。人们使用不同的药物治疗方案来清除它,但疾病会复发并产生更强的抗药性,从而降低了治愈率。此外,这种细菌现在呈现出急剧上升的多重耐药水平,需要反复进行治疗。与传统疗法相比,合成药物的副作用是支持非药物治疗的另一个重要因素。常用抗胃溃疡药物最显著的副作用包括恶心、呕吐和腹泻。以前,胃溃疡一直通过草药疗法和益生菌等辅助疗法进行治疗。摄入益生菌时,宿主会体验到一些可能因改变消化系统中的细菌菌群而带来的益处。此外,可以使用作用更强的化合物和植物提取物来治疗患者。在本文中,我们将探讨用于替代合成胃溃疡治疗药物的物质和药物。