Luo Su, Wu Ben-Hua, Wang Li-Sheng
Gastroenterology, Shenzhen People's Hospital, Second Clinical Medical College of Jinan University, China.
Gastroenterology, Shenzhen People's Hospital, Second Clinical Medical College of Jinan University.
Rev Esp Enferm Dig. 2025 Aug;117(8):461-462. doi: 10.17235/reed.2024.10506/2024.
Duodenal-type follicular lymphoma (D-FL) is a special type of follicular lymphoma, which tends to occur in the descending segment of the duodenum. The lesion is mostly limited to the mucosal layer. The treatment approach for D-FL has not been clearly established and the watch and wait (WW) approach is generally recommended as a major option. Since D-FL may be transformed into a more serious type of lymphoma, it is of clinical significance to explore active treatment methods. We diagnosed and successfully treated a case of D-FL with Endoscopic submucosal dissection (ESD). Because D-FL is limited to mucosa in the descending segment of the duodenum, ESD can completely dissect the lesion to achieve the purpose of complete resection. Compared with the WW, the method of WW after endoscopic therapy is more active, safe and effective.
十二指肠型滤泡性淋巴瘤（D-FL）是滤泡性淋巴瘤的一种特殊类型，倾向于发生在十二指肠降段。病变大多局限于黏膜层。D-FL的治疗方法尚未明确确立，一般推荐观察等待（WW）方法作为主要选择。由于D-FL可能转变为更严重的淋巴瘤类型，探索积极的治疗方法具有临床意义。我们通过内镜黏膜下剥离术（ESD）诊断并成功治疗了1例D-FL。因为D-FL局限于十二指肠降段的黏膜，ESD能够完整剥离病变以达到完全切除的目的。与观察等待相比，内镜治疗后观察等待的方法更积极、安全且有效。
