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种子多糖-铜纳米复合材料:绿色环境与抗菌研究的创新解决方案。

seed polysaccharide-copper nanocomposite: An innovative solution for green environment and antimicrobial studies.

作者信息

Majeed Hammad, Ahmad Khalil, Bibi Sadia, Iftikhar Tehreema, Ibrahim Mohamed M, Ruby Tahira, Mersal Gaber A M, El-Bahy Zeinhom M, Qureshi Khizar, Arif Muhammad, Naseem Khalida, Shaheen Shabnum, Bhatti Haq Nawaz

机构信息

Department of Chemistry, University of Management and Technology (UMT), Sialkot Campus, 51310, Pakistan.

Department of Chemistry, Emerson University Multan (EUM), Multan, 60000, Punjab, Pakistan.

出版信息

Heliyon. 2024 May 9;10(10):e30927. doi: 10.1016/j.heliyon.2024.e30927. eCollection 2024 May 30.

Abstract

The purpose of this study was to synthesize ecofriendly nano-composite in which agricultural waste (seeds of was used to synthesize tamarind seed polysaccharides (TSP) and its composite with copper nanoparticles (Cu-NPs) for the purpose of green and clean environment as well as reduction of green-house gases. Confirmation of extracted TSP, synthesized nanocomposite was carried out using FTIR, SEM, PXRD and EDX techniques. In FTIR analysis TSP gives a strong broad peak at 3331 cm due to -OH group and in case of composite its intensity is reduced which might be due to the interactions between -OH and Cu ions. SEM analysis gives that TSP have irregular and rough surface while Cu-NPs exhibited spherical morphology and composite showed clustering of spherical shape to rough surface. EDX analysis quantitatively represented copper having atomic ratio 0.57 % which confirms the synthesis of composite. Furthermore, synthesized composite demonstrated excellent antibacterial activity against gram-positive ( and gram-negative bacteria () even greater than standard medicine (ciprofloxacin). From this study it was revealed that agriculture waste can be utilized to make environment green as well as synthesized composite from agricultural waste seed also displayed excellent antimicrobial activities which directs that they can be utilized in medical field. This study aims to assess the antimicrobial properties of the nanocomposite, aiming to contribute to the development of effective antimicrobial agents. Through these objectives, the research seeks to bridge the gap between green technology and antimicrobial efficacy, offering a promising avenue for both environmental conservation and healthcare advancements.

摘要

本研究的目的是合成生态友好型纳米复合材料,其中利用农业废弃物(罗望子种子)合成罗望子种子多糖(TSP)及其与铜纳米颗粒(Cu-NPs)的复合材料,以实现绿色清洁环境并减少温室气体排放。使用傅里叶变换红外光谱(FTIR)、扫描电子显微镜(SEM)、粉末X射线衍射(PXRD)和能量色散X射线光谱(EDX)技术对提取的TSP和合成的纳米复合材料进行了表征。在FTIR分析中,由于-OH基团,TSP在3331 cm处出现一个强宽峰,而在复合材料中其强度降低,这可能是由于-OH与铜离子之间的相互作用。SEM分析表明,TSP具有不规则且粗糙的表面,而Cu-NPs呈现球形形态,复合材料显示出从球形到粗糙表面的聚集。EDX分析定量显示铜的原子比为0.57%,这证实了复合材料的合成。此外,合成的复合材料对革兰氏阳性菌( )和革兰氏阴性菌( )表现出优异的抗菌活性,甚至优于标准药物(环丙沙星)。从这项研究中可以看出,农业废弃物可用于绿化环境,并且由农业废弃物种子合成的复合材料也表现出优异的抗菌活性,这表明它们可用于医疗领域。本研究旨在评估纳米复合材料的抗菌性能,旨在为开发有效的抗菌剂做出贡献。通过这些目标,该研究旨在弥合绿色技术与抗菌功效之间的差距,为环境保护和医疗保健进步提供一条有前景的途径。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bea7/11108828/05c4b08346a9/gr1.jpg

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