Memic Samir, Kaple Claire E, Cadnum Jennifer L, Donskey Curtis J
Department of Systems Biology, Case Western Reserve University School of Medicine, Cleveland, Ohio.
Research Service, Louis Stokes Cleveland VA Medical Center, Cleveland, Ohio.
Pathog Immun. 2024 May 17;9(1):156-167. doi: 10.20411/pai.v9i1.683. eCollection 2024.
Technologies that provides safe and effective decontamination of surfaces and equipment between episodes of manual cleaning could be an important advance in efforts to prevent transmission of the emerging fungal pathogen .
We tested the efficacy of a novel wall-mounted far ultraviolet-C (UV-C) light technology that delivers far UV-C, when people are not detected within the field of illumination, against isolates from clades I, II, III, and IV using a quantitative disk carrier test method. In an equipment room, we examined the efficacy of the technology in reducing an isolate of from clade IV inoculated on multiple sites on portable devices.
The far UV-C technology reduced isolates from all 4 clades of by >3 log colony-forming units (CFU) aſter an 8-hour exposure on steel disks. For the clade IV isolate, similar reductions were achieved on glass and plastic carriers. In the equipment room, the technology reduced inoculated on multiple sites on portable equipment by >2 log CFU in 4 hours.
The far UV-C technology could be useful for decontamination of surfaces and equipment between episodes of manual cleaning. Additional studies are needed to evaluate the use of the technology in clinical settings.
在人工清洁期间,能够对表面和设备进行安全有效去污的技术可能是预防新型真菌病原体传播工作中的一项重要进展。
我们使用定量圆盘载体测试方法,测试了一种新型壁挂式远紫外线-C(UV-C)光技术的效果,该技术在照明区域内未检测到人员时可发出远紫外线-C,用于对抗来自I、II、III和IV进化枝的分离株。在一个设备间,我们检查了该技术在减少接种于便携式设备多个部位的IV进化枝分离株方面的效果。
在钢盘上暴露8小时后,远紫外线-C技术使来自所有4个进化枝的分离株减少了超过3个对数菌落形成单位(CFU)。对于IV进化枝分离株,在玻璃和塑料载体上也实现了类似的减少。在设备间,该技术在4小时内使接种于便携式设备多个部位的分离株减少了超过2个对数CFU。
远紫外线-C技术可用于在人工清洁期间对表面和设备进行去污。需要进一步研究以评估该技术在临床环境中的应用。