Zhang Yunyan, He Tong-Chuan, Zhang Hongmei
Chongqing Key Laboratory for Oral Diseases and Biomedical Sciences, The Affiliated Hospital of Stomatology, Chongqing Medical University, Chongqing, China.
Department of Pediatric Dentistry, The Affiliated Hospital of Stomatology, Chongqing Medical University, Chongqing, China.
Pediatr Discov. 2024 Mar;2(1). doi: 10.1002/pdi3.38. Epub 2023 Nov 3.
Periodontitis is a chronic inflammatory disease caused by plaque biofilm which shares risk factors with systemic chronic diseases such as diabetes, cardiovascular disease, and osteoporosis. Many studies have found increased prevalence and rate of progression of periodontal disease in children with common metabolic disorders. Although the causal relationship and specific mechanism between them has not been determined yet. The aim of this paper is to progress on the impact of metabolic disorders on periodontal health in children and the underlying mechanisms, which provides new evidences for the prevention and intervention of metabolic disorders and periodontitis in children.
牙周炎是一种由菌斑生物膜引起的慢性炎症性疾病，它与糖尿病、心血管疾病和骨质疏松症等全身性慢性疾病具有共同的危险因素。许多研究发现，患有常见代谢紊乱的儿童牙周疾病的患病率和进展速度有所增加。尽管它们之间的因果关系和具体机制尚未确定。本文旨在探讨代谢紊乱对儿童牙周健康的影响及其潜在机制，为儿童代谢紊乱和牙周炎的预防及干预提供新的证据。
