Department of Occupational Medicine, School of Medicine, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.
Department of Internal Medicine, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Ethiop J Health Sci. 2023 Sep;33(5):903-912. doi: 10.4314/ejhs.v33i5.20.
Diaphragmatic ultrasound is increasingly used to assess patients with Chronic Obstructive Pulmonary Disease (COPD). The present study aims to investigate diaphragmatic dysfunction in COPD patients through a systematic review and meta-analysis.
In December 2022,The researchers studied four international databases such as Medline/PubMed, ProQuest, ISI/WOS, and Scopus. Joanna Briggs Institute (JBI) checklist was used to review and control the quality of articles.
Finally, 6 articles were included in the analysis. Based on the meta-analysis results, forced expiratory volume (FEV1) was significantly lower in COPD patients compared to the control group (Hedges's g= -2.99, 95 % CI -4.78, -1.19; P =0.001). Forced vital capacity (FVC) was significantly lower in COPD patients compared to the control group (Hedges's g= -1.12, 95 % CI -1.91, - 0.33; P =0.005). COPD patients had significantly lower FEV1/FVC than the control group (Hedges's g= -1.57, 95 % CI -2.33, -0.81; P <0.001).
The present study showed that the diaphragm ultrasound (DUS) method could identify the difference in FEV1, FVC, and FEV1/FVC indices in two groups of COPD patients and healthy people.
膈肌超声在评估慢性阻塞性肺疾病(COPD)患者方面的应用越来越多。本研究旨在通过系统评价和荟萃分析来探讨 COPD 患者膈肌功能障碍。
研究人员于 2022 年 12 月检索了 Medline/PubMed、ProQuest、ISI/WOS 和 Scopus 等 4 个国际数据库,采用 Joanna Briggs 研究所(JBI)清单对纳入的文献进行评价和质量控制。
最终纳入 6 篇文献进行分析。基于荟萃分析结果,COPD 患者的用力呼气量(FEV1)显著低于对照组(Hedges's g=-2.99,95%CI-4.78,-1.19;P=0.001)。COPD 患者的用力肺活量(FVC)显著低于对照组(Hedges's g=-1.12,95%CI-1.91,-0.33;P=0.005)。COPD 患者的 FEV1/FVC 显著低于对照组(Hedges's g=-1.57,95%CI-2.33,-0.81;P<0.001)。
本研究表明,膈肌超声(DUS)方法可识别 COPD 患者与健康人群的 FEV1、FVC 和 FEV1/FVC 等指标的差异。