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膈肌超声在慢性阻塞性肺疾病(COPD)患者中的优势:系统评价和荟萃分析。

Diaphragmatic Ultrasound Advantages in Chronic Obstructive Pulmonary Disease (COPD) Patients: A Systematic Review and Metaanalysis.

机构信息

Department of Occupational Medicine, School of Medicine, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.

Department of Internal Medicine, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.

出版信息

Ethiop J Health Sci. 2023 Sep;33(5):903-912. doi: 10.4314/ejhs.v33i5.20.

Abstract

BACKGROUND

Diaphragmatic ultrasound is increasingly used to assess patients with Chronic Obstructive Pulmonary Disease (COPD). The present study aims to investigate diaphragmatic dysfunction in COPD patients through a systematic review and meta-analysis.

METHODS

In December 2022,The researchers studied four international databases such as Medline/PubMed, ProQuest, ISI/WOS, and Scopus. Joanna Briggs Institute (JBI) checklist was used to review and control the quality of articles.

RESULTS

Finally, 6 articles were included in the analysis. Based on the meta-analysis results, forced expiratory volume (FEV1) was significantly lower in COPD patients compared to the control group (Hedges's g= -2.99, 95 % CI -4.78, -1.19; P =0.001). Forced vital capacity (FVC) was significantly lower in COPD patients compared to the control group (Hedges's g= -1.12, 95 % CI -1.91, - 0.33; P =0.005). COPD patients had significantly lower FEV1/FVC than the control group (Hedges's g= -1.57, 95 % CI -2.33, -0.81; P <0.001).

CONCLUSION

The present study showed that the diaphragm ultrasound (DUS) method could identify the difference in FEV1, FVC, and FEV1/FVC indices in two groups of COPD patients and healthy people.

摘要

背景

膈肌超声在评估慢性阻塞性肺疾病(COPD)患者方面的应用越来越多。本研究旨在通过系统评价和荟萃分析来探讨 COPD 患者膈肌功能障碍。

方法

研究人员于 2022 年 12 月检索了 Medline/PubMed、ProQuest、ISI/WOS 和 Scopus 等 4 个国际数据库,采用 Joanna Briggs 研究所(JBI)清单对纳入的文献进行评价和质量控制。

结果

最终纳入 6 篇文献进行分析。基于荟萃分析结果,COPD 患者的用力呼气量(FEV1)显著低于对照组(Hedges's g=-2.99,95%CI-4.78,-1.19;P=0.001)。COPD 患者的用力肺活量(FVC)显著低于对照组(Hedges's g=-1.12,95%CI-1.91,-0.33;P=0.005)。COPD 患者的 FEV1/FVC 显著低于对照组(Hedges's g=-1.57,95%CI-2.33,-0.81;P<0.001)。

结论

本研究表明,膈肌超声(DUS)方法可识别 COPD 患者与健康人群的 FEV1、FVC 和 FEV1/FVC 等指标的差异。

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