Department of Electrical & Computer Engineering, Baylor University, Waco, TX 76798, USA.
Biosensors (Basel). 2024 May 15;14(5):249. doi: 10.3390/bios14050249.
The demand for easy-to-use, affordable, accessible, and reliable technology is increasing in biological, chemical, and medical research. Microfluidic devices have the potential to meet these standards by offering cost-effective, highly sensitive, and highly specific diagnostic tests with rapid performance and minimal sample volumes. Traditional microfluidic device fabrication methods, such as photolithography and soft lithography, are time-consuming and require specialized equipment and expertise, making them costly and less accessible to researchers and clinicians and limiting the applicability and potential of microfluidic devices. To address this, researchers have turned to using new low-cost materials, such as double-sided tape for microfluidic device fabrication, which offers simple and low-cost processes. The innovation of low-cost and easy-to-make microfluidic devices improves the potential for more devices to be transitioned from laboratories to commercialized products found in stores, offices, and homes. This review serves as a comprehensive summary of the growing interest in and use of double-sided tape-based microfluidic devices in the last 20 years. It discusses the advantages of using double-sided tape, the fabrication techniques used to create and bond microfluidic devices, and the limitations of this approach in certain applications.
在生物、化学和医学研究中,人们对易用、经济实惠、易于获取和可靠的技术的需求正在增加。微流控设备具有提供经济高效、高灵敏度和高特异性诊断测试的潜力,具有快速的性能和最小的样品量。传统的微流控设备制造方法,如光刻和软光刻,耗时且需要专用设备和专业知识,因此成本高,研究人员和临床医生难以获得,限制了微流控设备的适用性和潜力。为了解决这个问题,研究人员已经开始使用新的低成本材料,例如双面胶带,用于微流控设备制造,这种方法提供了简单且低成本的工艺。低成本和易于制造的微流控设备的创新提高了更多设备从实验室过渡到商店、办公室和家庭中商业化产品的潜力。本文综述了过去 20 年来,人们对基于双面胶带的微流控设备日益增长的兴趣和使用。它讨论了使用双面胶带的优点、用于创建和键合微流控设备的制造技术,以及在某些应用中这种方法的局限性。